What are the speakers talking about?

M：I have to provide a summary of this week’s sales to the directors in five minutes, but I can’t seem to locate the report I got from John anywhere. Have you seen it by any chance?
W：I remember Mr. Sato saying that he wanted to read it over earlier. Why don’t you go and ask his secretary if it’s on his desk?
M：Yes, that’s right. I completely forgot that he had asked me to let him see it. I don’t know what it is, but I am so absent-minded these days.
W：Well, I think it’s because you are working too hard. You know, you really need to take it easy, Mike. I heard that people in their 40s have to be really careful because they are most vulnerable to heart attacks. You really should learn to relax.
Number 41.What are the speakers talking about?
Number 42.What does the woman advise the man to do?
Number 43.How old is the man most likely?