首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
考研
Status of Gene Therapy At 18, Ashanthi Desilva of suburban Cleveland is a living symbol of one of the greater intellectual a
Status of Gene Therapy At 18, Ashanthi Desilva of suburban Cleveland is a living symbol of one of the greater intellectual a
admin
2013-05-04
72
问题
Status of Gene Therapy
At 18, Ashanthi Desilva of suburban Cleveland is a living symbol of one of the greater intellectual achievements of the 20th century. Born with an extremely rare and usually fatal disorder that left her without a functioning immune system (the "bubble-boy disease", named after an earlier victim who was kept alive for years in a sterile plastic ten), she was treated beginning in 1990 with a revolutionary new therapy that sought to correct the defect at its very source, in the genes of her white blood cells. It worked. Although her last gene-therapy treatment was in 1992, she is completely healthy with normal immune function, according to one of the doctors who treated her, W. French Anderson of the University of Southern California. Researchers have long dreamed of treating diseases from hemophilia to cancer by replacing mutant genes with normal ones. And the dreaming may continue for decades more. "There will be a gene-based treatment for essentially every disease," Anderson says, "within 50 years."
It’s not entirely clear why medicine has been so slow to build on Anderson’s early success. The National Institutes of Health budget office estimates it will spend $ 432 million on gene-therapy research in 2005, and there is no shortage of promising leads. The therapeutic genes are usually delivered through viruses that don’t cause human disease. "The virus is sort of like a Trojan Horse," says Ronald Crystal of New York Presbyterian/ Weill Cornell Medical College. "The cargo is the gene. "
At the University of Pennsylvania’s Abra-mson Cancer Center, immunologist Carl June recently treated HIV patients with a gene intended to help their cells resist the infection. At Cornell University, researchers are pursuing gene-based therapies for Parkinson’s disease and a rare hereditary disorder that destroys children’s brain cells. At Stanford University and the Children’s Hospital of Philadelphia, researchers are trying to figure out how to help patients with hemophilia who today must inject themselves with expensive clotting drugs for life. Animal experiments have shown great promise.
But somehow, things get lost in the translation from laboratory to patient. In human trials of the hemophilia treatment, patients show a response at first, but it fades over time. And the field has still not recovered from the setback it suffered in 1999, when Jesse Gelsinger, an 18-year-old with a rare metabolic disorder, died after receiving an experimental gene therapy at the University of Pennsylvania. Some experts worry that the field will be tarnished further if the next people to benefit are not patients but athletes seeking an edge. This summer, researchers at the Salk Institute in San Diego said they had created a " marathon mouse" by implanting a gene that enhances running ability; already, officials at the World Anti-Doping Agency are preparing to test athletes for signs of " gene doping". But the principle is the same, whether you’re trying to help a healthy runner run faster or allow a muscular-dystrophy patient to walk. "Everybody recognizes that gene therapy is a very good idea," says Crystal. "And eventually it’s going to work. "
Anderson’s early success has______.
选项
A、greatly speeded the development of medicine
B、brought no immediate progress in the research of gene-therapy
C、promised a cue to every disease
D、made him a national hero
答案
B
解析
事实细节题。文章第二段第一句It’s not entirely clear why medicine has been so slow to build on Anderson’s early success,所以选[B]。
转载请注明原文地址:https://kaotiyun.com/show/9Cd4777K
0
考研英语一
相关试题推荐
Technologyistheapplicationofscientificmethodandknowledgetoindustrytosatisfyourmaterialneedsandwants.Thisresul
Technologyistheapplicationofscientificmethodandknowledgetoindustrytosatisfyourmaterialneedsandwants.Thisresul
Themainideathispassagediscussesis_______.Thepurposeoftheexperimentintroducedinthelastparagraphis______.
Oneofthemostfashionabletreatmentsfordisease,genetherapy,hassofarmadelittleheadwayintacklingoneofthemostmod
(46)Itmustbestressedthatacharacteristicaspectofthepresenttimeisthatscienceisexercisingadecisiveinfluenceont
Theconceptofpersonalchoiceinrelationtohealthbehaviorsisanimportantone.Anestimated90percentofallillnessmayb
Theconceptofpersonalchoiceinrelationtohealthbehaviorsisanimportantone.Anestimated90percentofallillnessmayb
ThedateisJanuary18,2008.Youareamemberofthestudentunionofauniversity.Writeamemorandumtotheheadofthestude
TheauthordoesnotincludeamongthesciencesthestudyofThetitlewhichbestexpressestheideaofthistextis
[A]Anti-virussoftwareoftenbouncesawarningbacktothesenderofaninfectede-mail,sayingthatthee-mailinquestioncan
随机试题
A、Heprefersshorterplaystothisone.B、Hedoesn’thavetogotoseethatplay.C、Hewouldn’tseetheplayasoftenasthewom
A.光面内质网大量增生B.前角蛋白细丝堆积C.增大的载有蛋白质的溶酶体D.线粒体肿胀、嵴消失肝细胞内Mallory小体
A.冲洗法B.熏洗法C.纳药法D.宫腔注射法E.腐蚀法
账务处理模块是以记账凭证为接口与其他功能模块有机连接在一起,构成完整的会计核算系统。()
国际服务贸易具体包括()方式。
下列关于预算编制方法的说法中,正确的有()。
请分析下面教学案例体现的教学原则和教学方法。一位教师在教一年级学生学习“两数相差多少的应用题”一课时,老师为了让小朋友们都能够亲身感受和体会到老师教给他们的“比”的方法的可靠性,于是利用一年级学生爱唱爱跳和对比赛等具有奖励性的活动感兴趣的性格特征设计了一
CPU在中断周期要完成的任务不包括()。
结合材料回答问题:材料1国务院新闻办公室11日发表的《中国的亚太安全合作政策》白皮书介绍了中国参与地区非传统安全合作的情况。白皮书说,2015年以来,中国继续积极参与和推动亚太救灾交流合作,主办多个国际会议和活动,并先后向马来西亚、缅甸
PASSAGETWOWhydidtheshopassistantleadtheelderlywomantofindtheDVDinsteadoffindingitforher?
最新回复
(
0
)