Cigarettes leave you with more than a smoky scent on your clothes and fingernails. A new study has found evidence tobacco 【M1】__

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问题     Cigarettes leave you with more than a smoky scent on your
clothes and fingernails. A new study has found evidence tobacco 【M1】______
use can chemically modify and effect the activity of genes known 【M2】______
to increase the risk of developing cancer. The finding may give
researchers a new tool to assessing cancer risk among people who 【M3】______
smoke.
    DNA isn’t destiny. Chemical compounds that affect the
functioning of genes can bind to our genetic material, turning
certain genes on or of. These so-called epigenetic modifications 【M4】______
can influence variety of traits, such as obesity and sexual 【M5】______
preference. Scientists have even identified specific epigenetic
patterns on the genes of people who smoke. None of the modified
genes has a direct link to cancer, therefore, making it unclear 【M6】______
whether these chemical alterations increase the risk of developing
the disease.
    In the new study, publishing in Human Molecular Genetics, 【M7】______
researchers analyzed epigenetic signatures in blood cells from 374
individuals enrolled in the European Prospective Investigation
into Cancer and Nutrition. EPIC, which it’s known, is a massive 【M8】______
study aimed at linking diet, lifestyle, and environmental factors to
the incident of cancer and other chronic diseases. Half of the 【M9】______
group consisted in people who went on to develop colon or breast 【M10】______
cancer 5 to 7 years after first joining the study, whereas the other
half remained healthy.
【M6】

选项

答案therefore—however

解析 逻辑错误。前文提到外基因会影响人的生理特点,而且科学家已经找到了吸烟人基因中的外基因模式,而该句中提到变异的基因与癌症并没有直接联系,因此前后是转折关系,而不是因果关系,要改为表示转折的副词however。
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