首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
A Food and Drug Administration(FDA)advisory committee has concluded that a novel new treatment can greatly help rheumatoid arthr
A Food and Drug Administration(FDA)advisory committee has concluded that a novel new treatment can greatly help rheumatoid arthr
admin
2018-04-28
53
问题
A Food and Drug Administration(FDA)advisory committee has concluded that a novel new treatment can greatly help rheumatoid arthritis patients.
The panel recommended approving Enbrel for use alone in patients who haven’ t responded to other drugs or in combination with methotrexate, a cancer drug that has been the main treatment for rheumatoid arthritis.
The FDA must make a final decision by early November, and the drug’ s maker says it could be on the market by year’ s end.
In rheumatoid arthritis, which affects 2.1 million Americans, the immune system attacks healthy joints. A major wrongdoer in this process is a protein called "tumor killing factor" , or TNF, which interacts with a special molecule, or TNF receptor, on cells’ surfaces.
To keep inflammation in check, cells normally release some receptors to mop up excess TNF, rendering it inactive. Apparently, rheumatoid arthritis patients don’t have enough free-floating TNF receptors.
Enbrel consists of genetically engineered TNF receptors. In a six-month study, 234 patients with advanced rheumatoid arthritis received one of two doses of Enbrel or a placebo(harmless substance given as if it were medicine)in twice-a-week injections. They took injections for six months. By the end, 40% of patients on the larger Enbrel dose saw symptoms, such as swelling and joint pain, cut in half. Only 5% on the placebo did that well. The main side effect was minor irritation at the injection site.
Because some TNF is needed for a normal immune response, there is at least a theoretical risk of infections or even cancer in patients who take Enbrel, so the FDA panel urged long-term safety studies.
Last week, the FDA approved Arava, an oral treatment for rheumatoid arthritis that is similar to methotrexate. While calling both Enbrel and Arava "potentially very important" , Brian Butcher, vice president for research at the Arthritis Foundation, notes they have been tested in relatively few patients.
Butcher says their safety should be closely monitored once they’ re widely available.
Which of the following might be an appropriate title for the text?
选项
A、TNF and Immune System
B、Enbrel versus Methotrexate
C、Arthritis Drug on Path to Approval
D、Study on Rheumatoid Arthritis
答案
C
解析
该题为主旨题。全文介绍一种治疗风湿性关节炎的新药恩利的药理作用以及可能造成的风险,并说明由于新药的风险,食品药品管理局对于审批十分谨慎,敦促进行长期的安全性研究。选项C“关节炎药物的审批之路”涵盖了文章的主要内容,为正确选项。选项A“肿瘤坏死因子和免疫系统”、选项B“恩利与甲氨蝶呤”和选项D“风湿性关节炎研究”都是文章涉及的部分内容,不足以全面概括文章,故选C。
转载请注明原文地址:https://kaotiyun.com/show/OSRd777K
本试题收录于:
公共英语四级笔试题库公共英语(PETS)分类
0
公共英语四级笔试
公共英语(PETS)
相关试题推荐
Thetimeonecanenjoyanumberofdifferentsportingactivitiesinthesportscenterisfrom______.
AccordingtothelatestresearchintheUnitedStatesofAmerica,menandwomentalksuchdifferentlanguagesthatitislikepe
Psychologistswhoadoptastrongbehavioristpositiondenythatemotionexperiencesaremattersforscientificinquiry.Incontr
Thetangohasprobablytraveledfurtherandgonethroughmorechangesthanalmost【21】______.Africanslavesbroughtthetan
Thetangohasprobablytraveledfurtherandgonethroughmorechangesthanalmost【21】______.Africanslavesbroughtthetan
Ifsustainablecompetitiveadvantagedependsonworkforceskills,Americanfirmshaveaproblem.Humanresourcemanagementisn
Inaninterviewlastmonth,FrankChurch,chairmanoftheSenatecommitteewhichisinvestigatingtheCIA,issuedanobliquebut
Studiesoftheeffectthatmakesmanyofusslumberorfeelsleepyduringthequeen’sSpeechonChristmasDayhaverevealedthat
Onlythreestrategiesareavailableforcontrollingcancer:prevention,screeningandtreatment.Lungcancercausesmoredeaths
随机试题
人民法院审判上诉、抗诉案件的审判组织形式是
下列不属于M型超声心动图基本波群的是
关于双胎,下列哪项是错误的
肝火犯肺属于
修改会计科目。科目编码为1122的科目辅助核算修改为“单位”,多币种核算修改为“核算所有币种”。
幼儿辨别几何图形由易到难的顺序是()
机构庞大、政企不分,滋生了官僚主义,助长了不正之风,也给财政带来了沉重的负担。()
根据以下资料,回答问题。2014年1—6月份全国房地产开发投资42019亿元,同比增长14.1%(扣除价格因素实际增长13.1%),增速比:1—5月份回落0.6个百分点,其中往年投资28689亿元,增长13.7%,增速回落0.9个百分点,占房地产
设y=f(x)有二阶连续导数,且满足xy“+3xy‘2=1-e-x.若f(x)在x=0处取得极值,问f(0)是极小值还是极大值?
ForgetMaryPoppins—aninetiesnanny(保姆)ismorelikelytoresembleMartinSmith,who,at22,isoneofthenewbreedofBritish
最新回复
(
0
)