首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
Growing concerns over the safety and efficacy of anti-depressant drugs prescribed to children have caught the eye of Congress an
Growing concerns over the safety and efficacy of anti-depressant drugs prescribed to children have caught the eye of Congress an
admin
2011-03-10
31
问题
Growing concerns over the safety and efficacy of anti-depressant drugs prescribed to children have caught the eye of Congress and the New York state attorney general. Now they’re becoming the catalyst for calls to reform the way clinical trials of all drugs are reported.
Pressure is already causing some changes within the pharmaceutical industry. And it has put the US Food and Drug Administration (FDA), which approves new drugs, in the hot seat. If reforms are carried out, they could bring an unprecedented level of transparency to drug research.
The solution now under consideration: a public database, or registry, of drug trials, where companies would post the results of those trials.
In congressional testimony Thursday, a spokesman for the American Medical Association endorsed the registry and said it should include information on each trial’s purpose and objective, its design, and the dates it begins and ends. If the trial is not completed, the registry should include an explanation.
While drug companies have been eager to make public any positive results of their trials, recent revelations suggest they’ve balked at divulging tests when the results are not what they’d hoped to see. The furor has centered around the use Of anti-depressants on children.
The industry has begun to make some moves to address the concerns about drug trials. Drug companies have agreed to set up a voluntary system of posting their drug trials on the Internet. But that seems unlikely to satisfy some members of Congress, who are expected to introduce legislation to establish a mandatory drug registry.
Last week, editors of a dozen influential medical journals announced that they would begin requiring drug companies to post a drug trial in a public database prior to accepting an article about it. Doctors rely on these articles to make treatment choices. The editors hope that the registry will force unfavorable drug studies, before kept secret, into the open.
Medical journals already had been tightening up on the authorship of their articles, insisting that authors declare if they had any conflicts of interest, such as any financial or other ties to the drug company, says Daniel Callahan, a director at the Hastings Center, a nonprofit bioethics research institute in Garrison, N.Y.
Information from previously undisclosed clinical trials could lower prices, reduce the number of badly designed trials, and help doctors considering the use of a drug for a non-approved purpose to know why it hasn’t been approved for that use.
Antidepressant drugs "have some serious side effects ... that seem to be much more common than people realize ... much more common than you might think from seeing drug ads and from reports on drug studies," says Joel Gurin, executive vice president of Consumer Reports. His magazine just finished a survey of readers showing a "dramatic shift from talk therapy to drug therapy for mental health problems" during the past decade. In 1995, less than half of people getting mental health treatment--40 percent--got drug therapy. Today 68 percent receive drug treatment, Mr. Gurin says.
Some studies coming to light show that antidepressants work no better than placebos. Even better than merely registering drug trials, Caplan (director of the Center for Bioethics at the University of Pennsylvania in Philadelphia) suggests, would be to require that a new drug not only be "safe and do what it’s supposed to do", but that it do it as well or better than other drugs already on the market. That, he says, would help push research into new areas and save money.
What is Caplan’s opinion in the last paragraph?
选项
A、Registry of drug trials is of no use.
B、We should make demands on new drugs besides registering drug trials.
C、To put requirements on new drugs is much more effective than registering drug trials.
D、A new drug must be safe and better than any other drugs already on the market.
答案
B
解析
最后一段中Caplan的观点是什么?caplan指出“Even better than merely registering…”,“merely”这个词暗示,说话者意思是不仅要登记药品临床试验结果还要保证新药品安全并至少和市场上现有的药品一样有效。
转载请注明原文地址:https://kaotiyun.com/show/PtYO777K
0
专业英语八级
相关试题推荐
Americansoftentrytosaythingsasquicklyaspossible,soforsomeexpressionsweusethefirstlettersofthewordsinstead
IftherewasonethingAmericanshadarighttoexpectfromCongress,itwasafederalplantohelptheelderlypayforprescrip
Themusicindustry,hurtbyadeclineinCDsalesandthecontinuedfreeswappingoffilesontheInternet,tookthedrasticact
AnavidBushsupporterwhoalreadyhas25shoppingmallstohisname,Congelhimselfisnotamanyouwouldexpecttoentertain
SecurityconcernshavepromptedthefederaldepartmentsofStateandHomelandSecuritytotightentheprocessforissuingvisas
A、AsitsaiditcouldleadtoWebsiteswithcontentharmful.B、Asitsaiditcouldbebeneficialforchildren.C、Asitsaidit
Underexistinglaw,anewdrugmaybelabeled,promoted,andadvertisedonlyforthoseconditionsinwhichsafetyandeffectiven
In1969,theNationalWildlifeFederationbegantorecordanindexofenvironmentalqualitywhichmeasuresprogressordeclinei
Computers,andespeciallyconnectingtotheInternet,provideuniqueopportunitiestoenhancescienceandmatheducation.Tak
随机试题
民主
患者,女,22岁。心悸、手抖、怕热、烦躁5个月,查体:轻度突眼,甲状腺I度肿大,心率130次/分,手指细震颤(+);T3、T4高于正常,TSH降低。该患者首选的治疗是
髋关节单纯滑膜结核或单纯骨结核早期及时治疗,其结果可能是髋关节结核,未经治疗常发生的畸形是
大秦艽汤的功用是()消风散的功用()
无行为能力的精神病人实施的侵害行为是()。
陈某向王某声称要购买80克海洛因,王某便从外地购买了80克海洛因。到达约定交货地点后,陈某掏出仿真手枪威胁王某,从王某手中夺取了80克海洛因。此后半年内,因没有找到买主,陈某一直持有80克海洛因。半年后,陈某将80克海洛因送给其毒瘾很大的朋友刘某,刘某因过
水闸()的作用是挡水,以减小闸门的高度。
根据现行国家标准《火力发电厂与变电站设计防火标准》(GB50229),燃煤电厂厂区应划分重点防火区域,某些重点防火区域应设置环形消防车道。则下列防火区域中,可不设置环形消防车道的是()。
中央预算的政府采购项目中,集中采购目录由()确定并公布。
•Readthearticleaboutfinance.•Choosethebestsentencetofilleachofthegaps.•Foreachgap8—12markoneletter(A—G)
最新回复
(
0
)