首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
A newly published AIDS study could open another front in the battle against HIV infection by showing that gene therapy can be us
A newly published AIDS study could open another front in the battle against HIV infection by showing that gene therapy can be us
admin
2010-07-06
69
问题
A newly published AIDS study could open another front in the battle against HIV infection by showing that gene therapy can be used to stop infected cells from spreading the deadly virus, researchers said.
In a test-tube experiment believed to be the first of its kind, researchers based at Children’s Hospital of Philadelphia were able to block the operation of the" tat "gene that allows HIV to spread throughout the body from infected cells.
Up to now, genetic AIDS research has concentrated on finding ways to help healthy cells withstand the ravages of the HIV virus that infects an estimated 16, 000 new victims a day, mainly in the developing world.
But by working with human cells already infected with HIV, the team was able to reduce the tat gene’s virus-replicating functions by 80 percent to 90 percent, according to findings published in the journal Gene Therapy.
That, researchers said, raises the possibility of a new gene therapy approach capable of supplementing the current drug-based treatment known as highly active anti-retroviral therapy, or HAART, which is used to stop HIV infection from becoming full-blown AIDS.
In recent studies, HAART has proved to be a costly drug regimen that poses serious side effects for HIV patients while delivering questionable results.
"This is proof of the concept that HIV replication could be inhibited by a genetic approach, though we’re not at 100 percent yet, "said Dr. Stuart Starr, a study coauthor and chief of immunologic infectious diseases at Children’s Hospital.
"Everyone thinks of an antiviral approach, or an immunologic approach to HIV. This adds another option into the equation that could become more important as other options prove not to be totally successful."
Key to the study was an artificially produced" antitat" gene provided by the Washington-based Research Institute for Genetic and Human Therapy.
Children’s Hospital researchers used a mouse retrovirus to deliver the antitat gene into HIV-infected U-1 and ACH-2 cells, which were developed in the lab from the tissues of living HIV patients.
They found that when the antitat protein combined with the tat gene, it successfully inhibited the gene’s operation without disturbing healthy cells or causing toxic side-effects.
The study, funded by a private foundation, also found that the introduction of the antitat gene prolonged the survival of immune-system cells called CD4 + T lymphocytes.
Start said researchers have entered preliminary discussions with a New England-based primate center ,where animal experiments could be carried out on infected macaque monkeys.
If animal experiments proved successful, the Children’s Hospital team would hope to have a gene therapy treatment ready for human clinical trials in three to four years.
The gene therapy differs from HAART in that______.
选项
A、HAART is presently employed as a drug-based treatment
B、the gene therapy plays a minor role in relation to HAART
C、the gene therapy can stop HIV infection from becoming full-blown AIDS
D、HAART may produce questionable results, while gene therapy will certainly not
答案
A
解析
文章第六段“最近的研究表明,HAART是一种昂贵的药物疗法”。因此A “目前,HAART是以药物为基础的疗法”是HAART与基因疗法的区别所在。B 基因疗法与HAART有一点联系C 基因疗法能够阻止艾滋病病毒引起全面的艾滋病病发;D HAART可能会产生令人怀疑的结果,而基因疗法肯定不会。
转载请注明原文地址:https://kaotiyun.com/show/QuDd777K
本试题收录于:
公共英语四级笔试题库公共英语(PETS)分类
0
公共英语四级笔试
公共英语(PETS)
相关试题推荐
Fordecades,postersdepictingrabbitswithinflamed,reddenedeyessymbolizedcampaignsagainstthetestingofcosmeticsonani
Ontheheelsofitsrecentdecisiontocriminalizeconsumerswhoripsongsfromalbumstheyhavepurchasedtotheircomputers(o
Duetohistoricalreasons,peopleintheCzechRepubliclacked________.Whatwasthepercentageofpeoplewhodidnotdonatebe
Payandproductivity,itisgenerallyassumed,shouldberelated.Buttherelationshipseemstoweaken【C1】________peoplegetold
Payandproductivity,itisgenerallyassumed,shouldberelated.Buttherelationshipseemstoweaken【C1】________peoplegetold
HowhavetheoncereasonablypricedholidaysinEuropebecometoAmericans?HowarepartofthedollarsthatChinaaccumulates
HowhavetheoncereasonablypricedholidaysinEuropebecometoAmericans?EconomistBivenssaystheBushadministrationtalks
TherecentsocialandeconomicchangesintheU.S.havegreatimpactonalltheAmericanhousingsystem.Peopleformcooperati
Whomightbethefirstspeaker(theman)?
Inthe1960stheWestCoastbecameanimportantcenterforrockmusic.LosAngelesandSouthernCaliforniaarefamousforsun
随机试题
DNA的一条链为5’…TTAGCA.…3’,其互补DNA链为()
具有祛风湿、利关节、降压、解毒功效的药物是
海漫的作用是继续消除水流余能,调整流速分布,确保下游河床免受有害冲刷。它应该具有的特性有()。
某电建公司承担某发电厂安装工程。主要工作包括:锅炉、汽机、发电机、变压器、开关设备、架空线、控制设备等的安装。其中架空线由电建公司按设计要求组织采购。在施工过程中油浸变压器突然出现火苗,现场施工人员即时采取了有效措施,避免了事故发生。考虑发电企业技术密集性
证券公司的业务执行部门负责融资融券业务的具体管理和运作,制定融资融券合同的标准文本,确定对单一客户和单一证券的授信额度。()
在工程网络计划中,判别关键工作的条件是()。
适宜性教学认为,幼儿教学包括两方面的事宜,年龄适宜和性别适宜。()
已知向量β=(α1,α2,α3,α4)T可以由α1=(1,0,0,1)T,α2=(1,1,0,0)T,α3=(0,2,—1,—3)T,α4=(0,0,3,3)T线性表出。把向量β分别用α1,α2,α3,α4和它的极大线性无关组线性表出。
ArecentBBCdocumentary,"TheTownThatNeverRetired",soughttoshowtheeffectsof【C1】______thestatepensionagebyputtin
Theyareregardedaschoresbybothsexes,butfall(1)_____ononlyone.ThelatestsurveyoftimeuseinAmericasuggestswomen
最新回复
(
0
)