首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
admin
2013-07-02
76
问题
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally raised blood pressure — causes heart attacks, strokes and a multitude of other nasty conditions. Around a third of Americans and Britons suffer from it. It is thus a worthy enemy and nailing its cause is a priority. Until now, this has mostly seemed to lie in the kidneys. But Hidefumi Waki and Julian Paton of Bristol University think they have gathered some valuable new intelligence by studying the brain.
In a previous experiment Dr Waki and Dr Paton had found that rodents(啮齿动物)with high blood pressure expressed some genes differently in an area of the brain, called the solitary nucleus(孤束核, which sets the body’s normal blood-pressure level. One of these genes was called "junctional adhesionmolecule-1" or JAM-1 for short. It is a molecule normally found in the walls of blood vessels that attracts clotting and immune cells — in other words, it causes inflammation(炎症). So the pair decided to look at JAM-1 in further depth.
They found that in rats with high blood pressure JAM-1 levels were raised not only in the brain but also the kidney, lungs and skeletal muscle. To find out whether this was the cause or effect of high blood pressure, they then transferred the JAM-1 gene into the solitary nucleus of normal rats. After two weeks, these rats suffered from higher blood pressure than rats that had not received the gene.
Previously, experts thought that high blood pressure was caused by the kidneys. The idea was that the kidneys failed to sense the blood pressure. This then caused the lungs to make a hormone that increases blood pressure, leading to a chain of events that raised pressure throughout the blood-vessel network. All blood-pressure-lowering drugs work by seeking to put this right. Yet blaming the kidneys cannot be the full explanation of what is going on, because only half the sufferers respond to blood-pressure-lowering drugs.
Although these findings are preliminary, they have far-reaching implications. Variations in the JAM-1 gene and its expression may explain why high blood pressure tends to run in families, although it is also caused by a poor diet. The finding also shows that the brain could increase the activity of the sympathetic nerves, the part of the nervous system involved in stress response. Ultimately, the finding could hasten the development of drugs that would attack hypertension at its source, stopping its deadly consequences in their tracks.
The experiment of transferring JAM-1 into the normal rats is intended to prove the relationship between high blood pressure and______.
选项
答案
the rise of JAM-1 levels
解析
由线索词transferring JAM-1定位至第三段第二句,文中说为了查明JAM-1水平增长和高血压的关系,他们就把JAM—l基因移植到正常老鼠的孤束核内。句中的this指上一句中的JAM—1 levels were raised。
转载请注明原文地址:https://kaotiyun.com/show/Y5n7777K
0
大学英语六级
相关试题推荐
Consumershadbetterchooseaproviderofacreditcardwith______.Ifyouoftentravelonbusiness,______.
A、ThecoffeemarketinBoston.B、Theroleofsupermarketsinthecoffeebusiness.C、AnewtrendintheUnitedStates.D、Theadve
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
A、Defeat.B、Indifference.C、Acceptance.D、Violation.C
Thefirststeptodefeatanenemyistopindownhisexactidentityandhowheoperates.Hypertension—chronic,abnormallyrais
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
随机试题
默认情况下,Word2010的_____中含有设定字体的命令。
Iregret(tospend)(so)muchmoney(on)acar(that)Ihardlydriveineverydaylife.
提示排卵已经发生的指标是
下述不符合原发性血色素沉着症的是
在会计软件中,()一般用来完成原始凭证和单据的扫描,并将扫描结果存入会计软件相关数据库中。
俗话说:“冬练三九,夏练三伏”。这是说勤奋的人在最冷的“三九天”和最热的“三伏天”里都坚持锻炼。下列不是“三伏天”最热的原因是:
在VisualFoxPro中,编译或连编生成的程序文件的扩展名不包括()。
以下叙述中正确的是
Whatistilemainideaoftilenews?
It______beverycoldhere,eveninMay.
最新回复
(
0
)