首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
admin
2013-07-02
112
问题
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally raised blood pressure — causes heart attacks, strokes and a multitude of other nasty conditions. Around a third of Americans and Britons suffer from it. It is thus a worthy enemy and nailing its cause is a priority. Until now, this has mostly seemed to lie in the kidneys. But Hidefumi Waki and Julian Paton of Bristol University think they have gathered some valuable new intelligence by studying the brain.
In a previous experiment Dr Waki and Dr Paton had found that rodents(啮齿动物)with high blood pressure expressed some genes differently in an area of the brain, called the solitary nucleus(孤束核, which sets the body’s normal blood-pressure level. One of these genes was called "junctional adhesionmolecule-1" or JAM-1 for short. It is a molecule normally found in the walls of blood vessels that attracts clotting and immune cells — in other words, it causes inflammation(炎症). So the pair decided to look at JAM-1 in further depth.
They found that in rats with high blood pressure JAM-1 levels were raised not only in the brain but also the kidney, lungs and skeletal muscle. To find out whether this was the cause or effect of high blood pressure, they then transferred the JAM-1 gene into the solitary nucleus of normal rats. After two weeks, these rats suffered from higher blood pressure than rats that had not received the gene.
Previously, experts thought that high blood pressure was caused by the kidneys. The idea was that the kidneys failed to sense the blood pressure. This then caused the lungs to make a hormone that increases blood pressure, leading to a chain of events that raised pressure throughout the blood-vessel network. All blood-pressure-lowering drugs work by seeking to put this right. Yet blaming the kidneys cannot be the full explanation of what is going on, because only half the sufferers respond to blood-pressure-lowering drugs.
Although these findings are preliminary, they have far-reaching implications. Variations in the JAM-1 gene and its expression may explain why high blood pressure tends to run in families, although it is also caused by a poor diet. The finding also shows that the brain could increase the activity of the sympathetic nerves, the part of the nervous system involved in stress response. Ultimately, the finding could hasten the development of drugs that would attack hypertension at its source, stopping its deadly consequences in their tracks.
The experiment of transferring JAM-1 into the normal rats is intended to prove the relationship between high blood pressure and______.
选项
答案
the rise of JAM-1 levels
解析
由线索词transferring JAM-1定位至第三段第二句,文中说为了查明JAM-1水平增长和高血压的关系,他们就把JAM—l基因移植到正常老鼠的孤束核内。句中的this指上一句中的JAM—1 levels were raised。
转载请注明原文地址:https://kaotiyun.com/show/Y5n7777K
0
大学英语六级
相关试题推荐
A、Spain.B、France.C、America.D、Germany.C短文提到TheUnitedStatesalsohasmoreofitspeopleatwork,在西方发达国家,美国人比欧洲人工作的时间长,故答案为[
A、ThecoffeemarketinBoston.B、Theroleofsupermarketsinthecoffeebusiness.C、AnewtrendintheUnitedStates.D、Theadve
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
A、Workitself.B、Careeradvancement.C、Thesymbolsofsuccess.D、Socialidentity.A文中关键句为“Careeristsarenotsomuchintoworka
Thefirststeptodefeatanenemyistopindownhisexactidentityandhowheoperates.Hypertension—chronic,abnormallyrais
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
随机试题
输卵管外侧游离端的结构是()
与犬尿石症形成无关的病因是()。
四环素牙外脱色效果不佳的原因为
脂肪酸合成的原料乙酰CoA从线粒体转移至胞液的途径是
在我国,对土地实行()。
关于主合同与从合同,下列表述中错误的有()。
传言某银行支行因为一笔违规批贷可能导致重大损失,于是记者王某找到他在该支行的朋友张某欲进行采访。在这种情况下,()。
《南方周末》2005年11月24日报道了一则《全国人大代表集中轮训学习如何代表民意》的新闻,报道称80余名第十届全国人大代表集中于深圳人民大厦学习如何审议工作报告、如何提高议案建议质量、和谐社会与法治、十一五规划辅导报告、加强全国人大的制度建设等问题。参训
昨天是小红的生日,后天是小伟的生日。他俩的生日距星期天同样远。如果上述断定为真,那么,今天是星期几?
请在文档中插入“℃”符号。℃
最新回复
(
0
)