首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally rais
admin
2013-07-02
45
问题
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally raised blood pressure — causes heart attacks, strokes and a multitude of other nasty conditions. Around a third of Americans and Britons suffer from it. It is thus a worthy enemy and nailing its cause is a priority. Until now, this has mostly seemed to lie in the kidneys. But Hidefumi Waki and Julian Paton of Bristol University think they have gathered some valuable new intelligence by studying the brain.
In a previous experiment Dr Waki and Dr Paton had found that rodents(啮齿动物)with high blood pressure expressed some genes differently in an area of the brain, called the solitary nucleus(孤束核, which sets the body’s normal blood-pressure level. One of these genes was called "junctional adhesionmolecule-1" or JAM-1 for short. It is a molecule normally found in the walls of blood vessels that attracts clotting and immune cells — in other words, it causes inflammation(炎症). So the pair decided to look at JAM-1 in further depth.
They found that in rats with high blood pressure JAM-1 levels were raised not only in the brain but also the kidney, lungs and skeletal muscle. To find out whether this was the cause or effect of high blood pressure, they then transferred the JAM-1 gene into the solitary nucleus of normal rats. After two weeks, these rats suffered from higher blood pressure than rats that had not received the gene.
Previously, experts thought that high blood pressure was caused by the kidneys. The idea was that the kidneys failed to sense the blood pressure. This then caused the lungs to make a hormone that increases blood pressure, leading to a chain of events that raised pressure throughout the blood-vessel network. All blood-pressure-lowering drugs work by seeking to put this right. Yet blaming the kidneys cannot be the full explanation of what is going on, because only half the sufferers respond to blood-pressure-lowering drugs.
Although these findings are preliminary, they have far-reaching implications. Variations in the JAM-1 gene and its expression may explain why high blood pressure tends to run in families, although it is also caused by a poor diet. The finding also shows that the brain could increase the activity of the sympathetic nerves, the part of the nervous system involved in stress response. Ultimately, the finding could hasten the development of drugs that would attack hypertension at its source, stopping its deadly consequences in their tracks.
The experiment of transferring JAM-1 into the normal rats is intended to prove the relationship between high blood pressure and______.
选项
答案
the rise of JAM-1 levels
解析
由线索词transferring JAM-1定位至第三段第二句,文中说为了查明JAM-1水平增长和高血压的关系,他们就把JAM—l基因移植到正常老鼠的孤束核内。句中的this指上一句中的JAM—1 levels were raised。
转载请注明原文地址:https://kaotiyun.com/show/Y5n7777K
0
大学英语六级
相关试题推荐
HowwereimmigrantsviewedbyU.S.Congressinearlydays?WhatdoesEdwardTelles’researchsayaboutMexican-Americans?
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
TheUnitedStatesDepartmentofEducationsaystherearemorethan2,400Americancollegesanduniversities.About100ofthese
ThenoiseofaleafblowerislouderinAmericathanthatinNewZealand.Hypertensioncanbecausedbythenoiselowerthan65
Thefirststeptodefeatanenemyistopindownhisexactidentityandhowheoperates.Hypertension—chronic,abnormallyrais
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
GeorgeHerbertMeadsaidthathumansaretalkedintohumanity.Hemeantthatwegainpersonalidentityaswecommunicatewithot
随机试题
某物流企业在仓库中对运输的物品进行定量化小包装,则这反映的企业物流的功能为()。
下列不属于发散性思维特征的是()
控制职能
历史唯物主义认为( )
A.社会政策B.目标人群对生活满意程度的感受C.目标人群的疾病状况D.目标人群的行为危险因素E.组织评估和资源评估属于行为诊断内容的是
随同商品出售单独计价的包装物成本应计入其他业务成本。()
在教学过程中,教师和学生是互为主导的关系。
从数据库类型上看,Access的类型是
A—feedbackJ—dataprocessingB—floppydiskK—datacaptureC—checkdigitL—cardreaderD—keyboardM—electroniccashE—flo
A、Inahotel.B、Inabookstore.C、Inagrocery.D、Inalibrary.A对话中女士提到她已经预订了一间可以看到海景的双人房,男士表示他来查一下,并问女士姓什么。由此推断,对话发生在酒店里。
最新回复
(
0
)