______is known to the world, Mark Twain is a great American writer.

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问题 ______is known to the world, Mark Twain is a great American writer.

选项 A、That
B、It
C、Which
D、As

答案D

解析句意：众所周知，马克吐温是一位伟大的美国作家。在本句中，“as”指代“Mark Twain is a great American writer”。

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