______an unexpected contingency, our opening of the new office in London will not be delayed.

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问题 ______an unexpected contingency, our opening of the new office in London will not be delayed.

选项 A、Prior to
B、However
C、In spite of
D、Yet

答案C

解析语法：介词1．B选项However是副词，不能连接句子，D选项Yet是连词，不能出现在句首。2．连词In spite of意为“尽管”，可接名词词组，因此(C)为正确选项。

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