______ any film before, his first attempt was a great success.

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问题 ______ any film before, his first attempt was a great success.

选项 A、Though having never directed
B、Despite he had never directed
C、As he had never directed
D、In spite of his never having directed

答案D

解析 关联词辨析题。In spite of意为“尽管,虽然”,后面接名词或名词性短语,引导出状语。A 没有主语或逻辑主语;C 是原因状语从句;B 中despite是介词,不能引导状语从句。
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