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  3. The curse of jet lag has struck most international travelers at one time or another — and anyone lucky enough to have avoided it

The curse of jet lag has struck most international travelers at one time or another — and anyone lucky enough to have avoided it

admin2012-02-02  53
问题     The curse of jet lag has struck most international travelers at one time or another — and anyone lucky enough to have avoided it will surely have suffered the equally unpleasant sleep-deprivation involved in an early-morning start. Nor, as shift workers know too, is it possible to escape by going to bed earlier the previous evening, and thus putting sleep in the bank. Sleepiness is controlled by the body’s internal biological clock, so an earlier bedtime just means several wakeful hours staring in frustration at a darkened ceiling.
    For years, some travelers and shift workers have sworn by melatonin (褪黑素). This is a hormone that regulates the biological clock. It is made in the brain by a structure called the pineal gland (松果体), as darkness sets in after sunset. Light is the one that keeps the biological clock in the same pace with solar time. The clock then tells the brain when to go to sleep. The theory of those who use melatonin is that an external dose of it can reset the clock, and thus cause the "go to sleep" signal to be sent at a more convenient moment. Melatonin can also increase sleepiness during the day, when the pineal gland is not producing it.
    This has resulted in a growing, and often unregulated, market in melatonin-supplement tablets. The pharmaceutical industry’s response to this seems to be: "If you can’t beat them, join them." A paper in this week’s Lancet, by Shantha Rajaratnam of the Harvard Medical School and his colleagues, reports two trials, funded by drug companies, of tasimelteon, a substance that binds to the same receptors in the brain as melatonin does, and which it is expected will have a similar effect.
    In the course of these trials, more than 400 people had their bedtimes brought forward by five hours in controlled conditions. Half an hour before lights out, a quarter of them were given common drug, while the remaining three-quarters were given varying doses of tasimelteon. Dr. Rajaratnam and his colleagues report that the new drug let people fall asleep faster at the unnaturally early time, and also allowed them to sleep longer than those given the common one.
Shantha Rajaratnam’s team finds that tasimelteon works______than melatonin.
选项
答案better
解析 题干是在对新药tasimelteon和老药melatonin的效果进行对比，故将本题出处定位在讲述新药效果的最后一段。该段最后一句提到，与the common one相比，新药可以让人们更快(faster)入睡，而且也可以让人们睡眠更长(longer)。通读文章后可知，这里的the common one指的就是老药melatonin。由faster和longer综合可知，新药的作用效果比老药好，所以答案是better。
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