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医学
A、It is stable at room temperature for several years. B、It is administered directly into the bloodstream. C、It delivers glucose
A、It is stable at room temperature for several years. B、It is administered directly into the bloodstream. C、It delivers glucose
admin
2018-02-26
26
问题
A team of Australian chemistry students have strengthened the chemical bonds of insulin to make it stable even at warm temperatures—a breakthrough that could simplify diabetes management. The finding could shed light on how insulin works and eventually lead to insulin pills, rather than injections or pumps.
Insulin needs to be kept cold because it is made of weak chemical bonds that degrade at temperatures above 40 degrees Fahrenheit, making it inactive. But using a series of chemical reactions, the research team, comprised of students from Monash University in Australia, replaced the unstable bonds with stronger, carbon-based ones.
The stronger bonds stabilize the insulin’s two protein chains without interfering with its natural activity, according to a story about the findings at SciGuru. The so-called "dicarba" insulins were stable at room temperature for several years, SciGuru says.
Even more promising is that the findings provide insight into how insulin works.
People with Type 1 and Type 2 diabetes do not produce enough insulin, whether it’s the result of an auto-immune disorder that stops producing it entirely (Type 1) or a condition brought on by other factors like obesity, in which the body can no longer use it properly (Type 2). Insulin is the mechanism that delivers glucose from the blood to the cells, so diabetics must take a synthetic form of the hormone.
When insulin unlocks cells to allow sugar to be taken up from the blood, the hormone’s shape changes — but no one is sure what the shape looks like. If researchers knew that shape, they could design smaller, less-complex versions of insulin that don’t use proteins.
Then it could be administered in pill form rather than directly into the bloodstream. Understanding the molecule’s chemical bonds is a step toward unlocking that shape, the researchers say.
21. What is the main idea of the talk?
22. Why does insulin need to be kept cold, according to the talk?
23. What makes the research more promising?
24. What is true about the new type of insulin?
25. What is unknown to the scientists, according to the talk?
选项
A、It is stable at room temperature for several years.
B、It is administered directly into the bloodstream.
C、It delivers glucose from blood to the cells.
D、It is more chemically complex.
答案
A
解析
此题为细节信息题。题目问下列哪一个有关新型胰岛素的说法是真的。根据原文信息可以得知:研究结果表明这种新型胰岛素可以在室温下放置几年(不变质),因而答案为A。
转载请注明原文地址:https://kaotiyun.com/show/sPT3777K
本试题收录于:
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