首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
British doctors are to launch a major clinical trial to investigate whether a common anti-depression drug could be a cheap and e
British doctors are to launch a major clinical trial to investigate whether a common anti-depression drug could be a cheap and e
admin
2018-04-15
41
问题
British doctors are to launch a major clinical trial to investigate whether a common anti-depression drug could be a cheap and effective treatment for the destructive condition motor neurone(运动神经元)disease.
The trial, which is due to start in January, will follow more than 200 patients with motor neurone disease over 18 months to see if those given daily lithium pills live longer. Lithium is already licensed for treating depression and other mental disorders, and is extremely cheap, costing just 48p for a packet of 20 pills.
The £1m trial follows the publication in February of a small study by Italian researchers which suggested that lithium could slow the progression of the disease dramatically. The study sparked a surge of interest in the drug among online patient groups, and some doctors now offer lithium "off-label", despite widespread uncertainty as to whether it works.
Nigel Leigh, director of the motor neurone disease care centre at King’s College London, who will lead the trial, said: "It is our responsibility and duty to carry out this trial because we have to consider every lead seriously, and where there is real uncertainty, resolve it swiftly. The results of the Italian trial are too dramatic to ignore."
Motor neurone disease destroys nerves in the brain that control movement, leaving patients locked in a failing body. There is currently no cure and half die within 14 months of being diagnosed. In the UK, there are about 5,000 people with the condition. Stephen Hawking, the 66-year-old Cambridge physicist, was diagnosed with a rare form of motor neurone disease 45 years ago. He is now almost completely paralysed, although, as with most other patients, his mind remains active.
Doctors are unsure precisely how lithium works, but its effectiveness as an anti-depression treatment is thought to be linked to its ability to slow down electrical activity in brain cells.
Doctors are now recruiting patients who experienced their first symptoms of the disease within the past six months to three years. Results from the trial are expected within two years. It will be considered a success if patients who are given the drug live 20% longer than those who receive a placebo(安慰剂). "It would be very nice if we show lithium arrests the disease but we’re not expecting that. We’re hoping for a three- to six-month increase in lifespan over the 18-month trial," said Leigh.
If the drug is effective, it could be given to thousands of patients immediately. But doctors advised patients against taking it until the trial was over. Taken unsupervised, it could put them at risk of side-effects including confusion, kidney failure and damage to the thyroid gland(甲状腺), they warned.
Patients who suffer the motor neurone disease usually _____.
选项
A、are physically and mentally inactive
B、are deprived of the ability to move
C、get their immune system damaged
D、cannot do without a wheelchair
答案
B
解析
原文该句中的control movement和locked等词表明患上运动神经元疾病的病人就会丧失活动的能力,这一点从该段最后一句提到的关于Stephen Hawking的例子可以加以证实,因此本题应选B。
转载请注明原文地址:https://kaotiyun.com/show/stT7777K
0
大学英语六级
相关试题推荐
NurseHomeVisits:ABoostforLow-IncomeParents[A]NursehomevisitorTammyBallardhashadsomememorableexperiencesinclos
TheEnglishnationalcharacterisdualistic:Oneaspectisconservative,theotherextroverted(性格外向的).Thepubisafineexample
TheEnglishnationalcharacterisdualistic:Oneaspectisconservative,theotherextroverted(性格外向的).Thepubisafineexample
Britishdoctorsaretolaunchamajorclinicaltrialtoinvestigatewhetheracommonanti-depressiondrugcouldbeacheapande
Jointhe"SleepChallenge"[A]Didyougetenoughsleeplastnight?Probablynot."Weareanationofsleep-deprivedwomen,"says
Jointhe"SleepChallenge"[A]Didyougetenoughsleeplastnight?Probablynot."Weareanationofsleep-deprivedwomen,"says
Ourbodiesexperienceanebbandflowofenergythroughouttheday.Thisiscalledacircadianrhythm,andithasbeenstudied【C
Ourbodiesexperienceanebbandflowofenergythroughouttheday.Thisiscalledacircadianrhythm,andithasbeenstudied【C
ShockTreatment[A]TheobjectiveofAmerica’sAffordableCareActof2010—commonlyknownasObamacare—wastoensurethatthe40m
随机试题
甲给猪喂食盐酸克仑特罗(瘦肉精),将猪肉卖给肉联厂和普通老百姓,甲不构成犯罪。
属于发动机可变配气相位系统的是_______。
下列不属于无形资产计价金额的是()
当x→1时,()
基因表达的基本调控点在
男性,35岁,上腹部挤压伤5小时,上腹部,腰部及右肩持续性疼痛,伴恶心,呕吐。查体,体温38.6℃上腹部肌紧张明显,有压痛,反跳痛(±),移动性浊音(-),肠鸣存在。血常规,白细胞18.6×109/L,中性粒细胞90%,怀疑胰腺损伤。为进一步确诊,
β一内酰胺是由四个原子组成,环的张力比较大,化学性质不稳定,易被β一内酰胺酶催化发生开环导致失活。β一内酰胺酶能抑制该酶的活性,保护青霉素的结构。下列药物属于β一内酰胺酶抑制剂的是()。
[*]
若整型变量a、b、c、d中的值依次为:1、4、3、2。则条件表达式a<b?a:c<d?c:d的值是()。
考生文件夹下存在一个数据库文件“samp3.accdb”,里面已经设计了表对象“tEmp”,窗体对象“fEmp”,报表对象“rEmp”和宏对象“mEmp”。试在此基础上按照以下要求补充设计:设置“fEmp”窗体上名为“bTitle”的标签文本显示为阴影
最新回复
(
0
)