首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
考研
A new study on mice uncovers some answers that could someday offer a powerful target for eliminating the recurrence of bad memor
A new study on mice uncovers some answers that could someday offer a powerful target for eliminating the recurrence of bad memor
admin
2014-05-20
26
问题
A new study on mice uncovers some answers that could someday offer a powerful target for eliminating the recurrence of bad memories in humans, especially known to those who suffer from post-traumatic stress disorder(PTSD: mental disorder caused by accidents of emergency).
"Fear memories are the most robust memories—they can last over a lifetime," says Nadine Gogol-la, a biologist at Harvard University and lead author on the paper published recently in the journal Science. "You can push them far back, but spontaneous recovery and relapses will happen. " Until now, science has been unable to stop this process—in humans or in mice.
By repeating the previously reported rat findings, Gogolla and her colleagues found that at some point during a young mouse’s development—between about 16 and 23 days postnatal—a molecular net of sorts is cast over a region of the brain called the amygdala, effectively crystallizing formerly changeable memories.
"It looks just like what you would expect from a fisherman’s net," says Gogolla of the protein matrix(a living part in which something is formed)under the microscope. "And it acts as a structural constraint on the cells. How it does that, nobody really knows. " But the result is that memories are held inside. What the researchers did learn was that by cutting that net—with an injection of an enzyme that digests the chains linking the matrix together—memories could be once again destabilized.
"The drug cuts the net into its pieces," Gogolla says, "just like when you cut the strings of a net and it falls apart. " Then, for a couple of weeks, the original youthful plasticity in the neuronal circuits of the amygdala is regained and any bad memory formed after the matrix digestion could be subsequently eliminated through "extinction" therapy, a common treatment during which a patient is presented with the original fear trigger but in a context that is not fearful. When the treatment was given after a mouse underwent fear conditioning, however, extinction was unable to cut out that memory completely.
"Because the treatment has to occur before a traumatic event, it’s hard to make it immediately available," notes Gogolla. " But it does help us in finding the underlying mechanisms. " Eventually, she hopes tools can be found that can be applied after fear—inducing experiences, and that translate from mice to humans. This would be welcome relief for the approximately 20 percent of all military personnel who have returned from Iraq and Afghanistan reporting symptoms of PTSD, not to mention for heartbroken couples.
According to Gogolla and her colleagues, fearful memories______.
选项
A、only appear in the amygdala
B、tend to form at a very early age
C、look like a fishing net in the brain
D、influence the growth of young mice
答案
B
解析
推理题。由题干关键词Gogolla and her colleagues定位至第三段。该段介绍了格古拉和她的同事们在研究中的发现:在幼年老鼠成长过程中的某个时刻,一张由分子构成的“网”覆盖了大脑中的某个区域,并有效地将此前具有可塑性的记忆结晶化了。老鼠成长过程中的这个特殊时期大约是在出生后16~23天之间,由此可推断:恐怖记忆在生物成长初期就形成了,故选项[B]为正确答案。
转载请注明原文地址:https://kaotiyun.com/show/ytO4777K
0
考研英语一
相关试题推荐
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
Ourape-menforefathershadnoobviousnaturalweaponsinthestrugglefor【1】intheopen.Theyhadneitherthepowerfulteethno
随机试题
皮质醇增多症中,下列哪些临床表现与蛋白质代谢有关
下列可用于抗晕动病的药物是
A.普萘洛尔B.去甲肾上腺素C.异丙肾上腺素D.多巴胺E.酚妥拉明广泛用于心律失常、心绞痛和高血压的药是
A、以患者作为受试对象的试验B、以人作为受试对象的试验C、人体试验时必须要做到真正的知情同意D、选择受试者的时候需遵循的E、保障受试者身心安全人体试验是
某市由于粮食价格上升带动饲料价格上涨,又发生了“生猪高热病”,养猪户由于猪价低而不愿意花钱给病猪治疗,致使该市大量肉猪死亡,养殖成本增加导致猪肉价格比去年同期上涨两倍。这就大大提高了猪肉深加工企业的成本,估计猪肉制品价格将有大幅度的提高。以下哪项
日记描述法
四阶行列式的值等于()
若已经声明了函数原型“voidfun(inta,doubleb=0.0);”,则下列重载函数声明中正确的是()。
Fewnaturaldangersaremorefearedthanavalanches.AvalanchesareafamiliarpartofEuropeanhistory.ParticularlyintheSwi
LessNews,MuchBetterA)Inthepastfewdecades,thefortunateamongushaverecognizedthehazardsoflivingwithanoverabund
最新回复
(
0
)