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  3. At the turn of the 20th century, Dutch physician Christiaan Eijkman showed that disease can be caused not only by microorganism

At the turn of the 20th century, Dutch physician Christiaan Eijkman showed that disease can be caused not only by microorganism

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问题     At the turn of the 20th century, Dutch physician Christiaan
Eijkman showed that disease can be caused not only by
microorganisms but by a dietary efficiency of certain substances【M1】______
now called vitamins. In 1909 German bacteriologist Paul Ehrlich
introduced the world’s first bactericide, a chemical designed to kill
specific kinds of bacteria with killing the patient’s cells as well.【M2】______
Following the discovery of penicillin in 1928 by British
bacteriologist Sir Alexander Fleming, antibiotics joined medicine’s
chemical armory, making the fight against bacterial infection
almost a routine matter. Antibiotics cannot act as viruses, but【M3】______
vaccines have been used to greatly effect to prevent some of the【M4】______
deadliest viral diseases. Smallpox, once a worldwide killer, was
completely eradicated by the late 1970s, and in the United States a【M5】______
number of polio cases dropped from 38,000 in the 1950s to less
than 10 a year by the 21st century.
    By the middle of the 20th century scientists believed they
were well on the way to treating, preventing, or eradicating many
of the most deadly infectious diseases that plagued humankind for【M6】______
centuries. And by the 1980s the medical community’s confidence【M7】______
in its ability to control the infectious diseases had been shaken by【M8】______
the emergency of new types of disease-causing microorganisms.【M9】______
New cases of tuberculosis developed, caused by bacteria strains
that were resistant to antibiotics. New, deadly infections on which【M10】______
there was no known cure also appeared, including the viruses that
cause hemorrhagic fever and the human immunodeficiency virus
(HTV), the cause of acquired immunodeficiency syndrome.
【M4】
选项
答案greatly一great
解析 语法错误。to great effect是固定搭配，意思为“有很大影响，起很大作用”。这里要注意的是，be used to do sth．后面所接的动词并不是effect，而是prevent。effect虽然也具备动词词性．但此处是作名词，和to great构成搭配。本句的意思是“抗生素不能对抗病毒，但是疫苗的使用在很大程度上能阻止一些极其致命的病毒性疾病。”
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