首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
考研
Fat: what is it good for? Absolutely nothing, or so you might think. But obesity seems to protect mice against a fatal form of m
Fat: what is it good for? Absolutely nothing, or so you might think. But obesity seems to protect mice against a fatal form of m
admin
2015-12-23
29
问题
Fat: what is it good for? Absolutely nothing, or so you might think. But obesity seems to protect mice against a fatal form of malaria—cerebral malaria. Working out how it has this effect might lead to new treatments for people.
Although obesity is now on the rise in the developing world, it has traditionally been seen as a malaise of the rich. In contrast, malaria tends to be regarded as a disease of the poor, so few people have studied how the two conditions affect each other. In mice meanwhile, there are signs that diabetes, which often affects obese people, might offer some protectioa against malaria.
To find out more about how obesity affects malaria in mice, Vincent Robert at the Institute for Development Research(IRD)in Paris, France, and colleagues injected 14 obese and 14 non-obese mice with the malaria parasite Plasmodium berghei. After six days, eight of the non-obese mice died from cerebral malaria, which causes coma and death in humans, and the rest died about two weeks later from severe anemia because the parasite had destroyed their red blood cells. In contrast, none of the obese mice showed signs of cerebral malaria. Although they all eventually succumbed to severe anemia and died 18 to 25 days after infection, anemia can be treated—so obesity did seem to offer mice some useful protection.
Exactly how the obese mice resist malaria is not clear, says Delphine Depoix from the Museum of Natural History in Paris, but there are several possibilities. One clue lies in a mutation in the gene coding for the leptin, a hormone produced by fat cells, which makes the mice obese, but also controls the immune response. Previous research has shown that obese mice with the leptin mutation often react to infections with a "Th2" rather man "Thl" response. As Thl in mice is thought to trigger the inflammation mat helps cerebral malaria to kill its victims, Depoix speculates mat me Th2 response might be protecting me obese mice. Another possible explanation is that the abnormally high blood sugar associated with obesity in both mice and people "might compensate" for the low blood sugar caused by severe malaria, says Depoix, allowing me mice to better cope with parasite infection.
Andrew Prentice of the London School of Hygiene and Tropical Medicine says that figuring out how me mice resist malaria will be crucial to developing new treatments for people with malaria. His colleague Christopher Whitty warns that any insights drawn from these results are preliminary: "Mouse models are always useful in raising hypotheses but cannot settle them as far as cerebral malaria is concerned."
To which of the following statements would Delphine Depoix most probably agree?
选项
A、The obese mice are likely to give reaction to infections with a "Thl "response.
B、The obese mice with the leptin mutation might be protected by "Th2" response.
C、The inflammation triggered by Th2 helps cerebral malaria to kill its victims.
D、Thl in mice kills mice in a direct way.
答案
B
解析
观点态度题。根据Delphine Depoix定位到第四段。研究发现,瘦素突变的肥胖老鼠经常对传染病做出Th2反应,而Th2反应可能保护肥胖的老鼠,故B项与之相符。A项“Thl”response与“通常对传染病做出Th2反应,而不是Thl反应”相悖;C项triggered by Th2与“Thl会诱发炎症”不符;文中提到,老鼠的Thl会诱发炎症。从而促使脑型疟置患者于死地,因此D项in a direct way错误。
转载请注明原文地址:https://kaotiyun.com/show/42sZ777K
0
考研英语一
相关试题推荐
Forallthesereasons,readingnewspapersefficiently,whichmeansgettingwhatyouwantfromthemwithoutmissingthingsyoune
Youhaveallhearditrepeatedthatmenofscienceworkbymeansofinductionanddeduction,thatbythehelpoftheseoperation
Itthereforebecomesmoreandmoreimportantthat,ifstudentsarenottowastetheiropportunities,therewillhavetobemuch
【F1】Mostpeopleknowthatawkwardfeelingwhenyoushuffleintoanelevatorwithotherpeopleandtrynottomakeeyecontact.【
Economics,asweknowit,isthesocialscienceconcernedwiththeproduction,distribution,exchange,andconsumptionofgoods
Sustainabledevelopmentisappliedtojustabouteverythingfromenergytocleanwaterandeconomicgrowth,andasaresultith
Thepublisher’stechniquesforbookpromotionhavebecomeincreasinglysophisticatedinalladvancedcountries.Thetypicaltrav
AsPhiladelphiagrewfromasmalltownintoacityinthefirsthalfoftheeighteenthcentury,itbecameanincreasinglyimport
CompaniesarelobbyinghardtoremovetheEU’straceabilityandlabelingpoliciesforproductscontainingGMingredients.Br
GivenalltheroilingdebatesabouthowAmerica’schildrenshouldbetaught,itmaycomeasasurprisetolearnthatstudentssp
随机试题
乳突双15°侧位又称为
天成公司是一家股份有限责任公司,其发起人是甲、乙、丙、丁、戊。公司设立方式为募集设立,由发起人向社会公开募集设立。董事会成员为5人,甲、乙、丙、丁、戊同时也是公司董事会成员。根据我国《公司法》的规定,下列选项中所描述的情况符合法律规定的是:()
限制管道径向位移,但允许轴向位移的支架称为()。
某合资企业从英国进口一批作为投资的机器设备,该企业委托A进出口公司对外签订进口合同,并代办进口手续,A公司与外商订货后,随即委托B公司具体办理货物运输事宜,同时委托C报关公司负责办理进口报关手续。根据这种情况,请指出下列出现在报关单栏目内的单位,错误的是(
国内信用证结算方式只适用于转账结算,不得支取现金。()(2010年)
在教育教学的细节中尊重学生的个别差异应做到()。
京剧、中医、国画被誉为中国的“三大国粹”,下列有关我国国粹的表述,不正确的是()。
三角形的三边长为2,x,9,其中x为奇数,则周长为().
•Readthearticlebelowaboutthemanagementoforiginalthinkers,andthequestionsontheoppositepage.•Foreachquestion
Forthispart,youareallowed30minutestowriteashortessayentitledBeGenerouswithYourCompliments.Youressayshouldi
最新回复
(
0
)