首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
At 18, Ashanthi DeSilva of suburban Cleveland is a living symbol of one of the great intellectual achievements of the 20th centu
At 18, Ashanthi DeSilva of suburban Cleveland is a living symbol of one of the great intellectual achievements of the 20th centu
admin
2011-01-02
41
问题
At 18, Ashanthi DeSilva of suburban Cleveland is a living symbol of one of the great intellectual achievements of the 20th century. Born with an extremely rare and usually fatal disorder that left her without a functioning immune system (the "bubble-boy disease", named after an earlier victim who was kept alive for years in a sterile plastic tent), she was treated beginning in 1990 with a revolutionary new therapy that sought to correct the defect at its very source, in the genes of her white blood cells. It worked. Although her last gene-therapy treatment was in 1992, she is completely healthy with normal immune function, according to one of the doctors who treated her, W. French Anderson of the University of Southern California. Researchers have long dreamed of treating diseases from hemophilia to cancer by replacing mutant genes with normal ones. And the dreaming may continue for decades more. "There will be a gene-based treatment for essentially every disease," Anderson says, "within 50 years. "
It’s not entirely clear why medicine has been so slow to build on Anderson’ s early success. The National Institutes of Health budget office estimates it will spend $ 432 million on gene-therapy research in 2005, and there is no shortage of promising leads. The therapeutic genes are usually delivered through viruses that don’ t cause human disease. "The virus is sort of like a Trojan horse," says Ronald Crystal of New York Presbyterian/Weill Cornell Medical College. "The cargo is the gene. "
At the University of Pennsylvania’s Abramson Cancer Center, immunologist Carl June recently treated HIV pa tients with a gene intended to help their cells resist the infection. At Cornell University, researchers are pursuing gene-based therapies for Parkinson’s disease and a rare hereditary disorder that destroys children’ s brain cells. At Stanford University and the Children’ s Hospital of Philadelphia, researchers are trying to figure out how to help patients with hemophilia who today must inject themselves with expensive clotting drugs for life. Animal experiments have shown great promise.
But somehow, things get lost in the translation from laboratory to patient. In human trials of the hemophilia treatment, patients show a response at first, but it fades over time. And the field has still not recovered from the setback it suffered in 1999, when Jesse Gelsinger, an 18-year-old with a rare metabolic disorder, died after receiving an experimental gene therapy at the University of Pennsylvania. Some experts worry that the field will be tarnished further if the next people to benefit are not patients but athletes seeking an edge. This summer, researchers at the Salk Institute in San Diego said they had created a "marathon mouse" by implanting a gene that enhances running ability; already, officials at the World Anti-Doping Agency are preparing to test athletes for signs of "gene doping". But the principle is the same, whether you’re trying to help a healthy runner run faster or allow a muscular-dystro-phy patient to walk. "Everybody recognizes that gene therapy is a very good idea," says Crystal. "And eventually it’s going to work. "
Anderson’s early success has
选项
A、greatly speeded the development of medicine
B、brought no immediate progress in the research of gene-therapy
C、promised a cure to every disease
D、made him a national hero
答案
B
解析
文章第二段一开头就说:“It’s not entirely clear why medicine has been so slow to build on Anderson’s early success.”从时间上来看,Anderson采用基因疗法的成功尝试已经是1990年的事情了,两相对照,可见他的成功没有让医学加速发展。因此正确答案为B。
转载请注明原文地址:https://kaotiyun.com/show/LdHd777K
本试题收录于:
公共英语五级笔试题库公共英语(PETS)分类
0
公共英语五级笔试
公共英语(PETS)
相关试题推荐
HowaTerribleBattleHelpedtoChangeEuropeNinetyyearsagoonasunnymorninginNorthernFrance,somethinghappenedtha
HowaTerribleBattleHelpedtoChangeEuropeNinetyyearsagoonasunnymorninginNorthernFrance,somethinghappenedtha
TheScienceofPersuasionIfleadershipconsistsofgettingthingsdonethroughothers,thenpersuasionisoneoftheleader
BeautyBeautyhasalwaysbeenregardedassomethingpraiseworthy.Almosteveryonethinksattractivepeoplearehappierandh
Aresultofnuclearexplosion,falloutisthedescentofminuteparticlesofradioactivematerialthroughtheatmosphere.
ThroughoutBritain’shistory,therehasbeennoguaranteethataninvasionwouldnothappen.Theenemywilluseeverymeanscon
SymptomsofPervasiveAnti-IntellectualismAmericanstodaydon’tplaceaveryhighvalueonintellect.Ourheroesareathl
Alllivingorganisms,regardlessoftheiruniqueidentity,havecertainlogical,chemical,andphysicalcharacteristicsincommo
TrafficJams—NoEndinSight1.Trafficcongestion(拥堵)affectspeoplethroughouttheworld.Trafficjamscausesmogindozens
DNAFingerprintingDNAisthegeneticmaterialfoundwithinthecellnucleiofalllivingthings.Inmammalsthestrandsof
随机试题
first/lstyear录音原文中的名词词组academicsuccess“学术上的成功”是对题目中的动词词组succeedacademically“在学术上取得成功”的同义替换。
德育、智育、体育、美育、劳动技术教育是全面发展教育的基本组成部分。下列关于全面发展教育的说法正确的有()
下列物质中毒可采用腹膜透析解救的是
A.病变常呈特征性带状分布:增生活跃的纤维组织、类骨组织、成熟骨组织B.由软骨膜、软骨帽及骨性基底构成C.由纤维组织及周边成排骨母细胞围绕的骨小梁构成D.由软骨样组织、黏液样组织和纤维组织构成E.呈分叶状,由胞质红染、含空泡的软骨细胞及透明软骨基质
急性心肌梗死的处理中,不正确的是
A.抑制RNA多聚酶B.抑制蛋白质合成C.抑制分枝菌酸合成D.抑制二氢叶酸合成酶E.抑制二氢叶酸还原酶PAS抗结核杆菌的作用原理是
公开招标采用公告的形式发布,邀请招标采用投标邀请书的形式发布,体现了两者()不同。
“小李并非既懂英语又懂俄语”,对这句话理解正确的是()。
什么是要素主义教育?
ReformandMedicalCosts[A]Americansaredeeplyconcernedabouttherelentlessriseinhealthcarecostsandhealthinsurancep
最新回复
(
0
)