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  3. In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.

In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.

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问题     In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.【C1】________. in 2012, MERS was identified. In 2019, SARS-CoV-2【C2】________.
    Hundreds of other coronaviruses are known to be【C3】________in bats and other animals. Scientists have warned that some of them could arise in the future and【C4】________infect people. Our current COVID-19 vaccines were specifically【C5】________for SARS-CoV-2, but what if a next-generation vaccine could protect【C6】________both known and unknown coronaviruses?
    Scientists at the Walter Reed Army Institute of Research are working on a so-called universal coronavirus vaccine. Dr. Kayvon Modjarrad is【C7】________the effort. They have developed a vaccine specifically for SARS-CoV-2, and found that the immune response that it【C8】________is active against all the variants, as well as other coronaviruses like SARS-CoV-1. And this gives them confidence that it can be a platform for the entire coronavirus family.
    The vaccine is known as SpFN, which combines nanoparticles from ferritins with coronavirus spike proteins. But making the vaccine wasn’t as【C9】________as attaching one protein to another. Modjarrad and his colleagues had to【C10】________which parts of the spike to attach to which type of ferritin and how to【C11】________the two proteins together. It took months of trying more than 200 different【C12】________. By June of last year, the team found one version that succeeded where others had failed. They then【C13】________the experimental vaccine in mice and monkeys.
    The team also turned to less【C14】________animals for testing. Working with scientists in India, they【C15】________horses with the vaccine to learn how strong the【C16】________response was. And they【C17】________with Helen Dooley at the University of Maryland to vaccinate sharks—which make special antibodies.
    The results are【C18】________. but animals aren’t people. The Army vaccine is now being tested in a small, early-stage trial in humans.【C19】________it works and is safe, it could lay the【C20】________for a universal coronavirus vaccine.
【C6】
选项 A、with
B、on
C、in
D、against
答案D
解析 空格处上下文为a next-generation vaccine could protect________both known and unknown coronaviruses，其中主语中心词为vaccine，宾语中心词为coronaviruses。由常识可知，疫苗的作用就是预防病毒感染，故谓语部分的意思应为“抵御；预防”，选项中只有against符合句意，protect与against搭配，意思即“抵抗，抵御”，因此选项D为答案。A项“和……；用……”，B项“在……之上”，C项“在……里”，都无法与protect构成表示“抵抗，抵御”的搭配，故排除。
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