Scientists say they have found a way to turn body fat into a better type of fat that burns off calories and weight The US Johns

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问题     Scientists say they have found a way to turn body fat into a better type of fat that burns off calories and weight The US Johns Hopkins team made the【C1】________in rats but believe the same could be done in humans, offering the hope of a new way to treat obesity.
    【C2】________the expression of a protein linked to【C3】________not only reduced the animals’ calorie intake and weight but also【C4】________their fat composition.
    Brown fat is【C5】________in babies, which they use as a【C6】________source to generate body heat,【C7】________calories at the same time. But as we age our brown fat largely【C8】________and gets replaced by "bad" white fat, which【C9】________sits as a spare tyre around the waist.
    "We will need a lot more work to tease this out, but it could offer a(n)【C10】________way to develop new treatments for obesity", an expert said.
    Experts have【C11】________that stimulating the body to make more brown fat【C12】________white fat could be a helpful way to control weight and【C13】________obesity and its related health problems. Various teams have been searching for a way to do this, and Dr Sheng Bi and colleagues at the Johns Hopkins University School of Medicine believe they may have cracked it. They designed an experiment to see【C14】________suppressing an appetite-stimulating protein called NPY would decrease body weight in rats. When they silenced NPY in the brains of the rats they found their appetite and food【C15】________decreased. Even when the rats were fed a very【C16】________, high-fat diet they still managed to keep more weight【C17】________than rats who had fully functioning NPY. The scientists then checked the fat【C18】________of the rats and found an interesting change had occurred. In the rats with silenced NPY expression, some of the bad white fat had been replaced with good brown fat.
    The researchers are【C19】________that it may be possible to achieve the same effect in people by injecting brown fat stem cells【C20】________the skin to burn white fat and stimulate weight loss.
【C19】

选项 A、persistent
B、hopeful
C、dubious
D、cautious

答案B

解析 上文提到该实验已经在老鼠身上产生了效果,下文说在人身上也可能产生同样的效果。此处表达研究人员的期望,故选B项hopeful“有希望的”。A项persistent通常用于某种状态或情形持续存在,特别是坏的或令人不悦的状态或情形,这里的主语为人,显然用法不对。C项dubious“半信半疑的”,根据第一段的最后一句“这有望给治疗肥胖带来新方法”,可知研究者是持相信态度的。D项cautious“谨慎的”,通过空格后的may be possible可看出,研究人员对此还是充满希望的。
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