Despite the fact that today viruses are known to cause cancer in animals and in certain plants, where exists a great reluctance

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问题     Despite the fact that today viruses are known to cause cancer
in animals and in certain plants, where exists a great reluctance 【M1】______
to accept viruses as been of importance in human cancer. Basic 【M2】______
biological phenomena generally does not differ strikingly as 【M3】______
one goes from one species to other. It should be recognized that 【M4】______
cancer is a biological problem and not a problem that is unique
for man. Cancer originates when a normal cell suddenly becomes
a cancer cell which multiplies widely and with apparent restraint. 【M5】______
Cancer cells originate in many different kinds of cell, but the
cancer cell usually continues to carry certain traits of the cell of
origin. The transformation of a normal cell to a cancer cell may 【M6】______
have more than one kind of cause, but there’s good reason to
consider the relationships exist between viruses and cancer.
    Since there’s no evidence which human cancer, as generally 【M7】______
experienced, is infectious, many person believe that because 【M8】______
viruses are infectious agents, they can possibly be of important in 【M9】______
human cancer. Furthermore, viruses and examples are known in
which a virus never kills its host can mutate to form a new strain 【M10】______
of virus that always kills its host. It does not seem unreasonable
to assume that an innocuous latent virus might mutate to form a
strain that causes cancer.
【M5】

选项

答案with—without

解析 根据上下文可知,这里说癌细胞大面积地繁殖(multiplies widely),那么应该是没有约束地生长,而with apparent restraint却与此相矛盾,故将with改为without。
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