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  3. Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

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问题    Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【C1】______be applied fairly randomly or carelessly, but nowadays many believe that effective therapies need to be【C2】______and tailored to genetic faults in each individual’s cancer.
   However, a personalized treatment disregards the most fundamental reason why it is difficult to cure cancers【C3】______: cancer cells adapt and evolve【C4】______treatment. Even drugs that are initially effective often have a【C5】______diminishing effect, as the biological systems blocked by the treatment spontaneously compensate【C6】______re-routing the cancer cells’ internal wiring,【C7】______the cancer’s ability to spread. To use an【C8】______, traffic hot spots in towns can cause major traffic jams, but smart drivers will quickly find other short cuts. Then, in the absence of "short cuts", evolution【C9】______: naturally arising mutant cancer cells that are【C10】______the targeted drug rapidly outgrow their disabled siblings and cancer comes back.
【C3】
选项 A、in the past
B、on the horizon
C、once for all
D、by no means
答案C
解析 in the past：在过去(与本句中的现在时矛盾)；on the horizon：马上出现；once for all：一劳永逸地，彻底；by no means：绝不。cure cancers once for all的含义是“根治癌症”。
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