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医学
Personalized genetic diagnosis and therapy say you’ re young and healthy, and you go in for a routine physical. Your doctor take
Personalized genetic diagnosis and therapy say you’ re young and healthy, and you go in for a routine physical. Your doctor take
admin
2013-11-30
60
问题
Personalized genetic diagnosis and therapy say you’ re young and healthy, and you go in for a routine physical. Your doctor takes a blood sample and has it shipped to a lab. There, a medical technologist places your serum sample on a glass chip the size of a postage stamp. That gene chip might contain up to 50,000 microscopic spots—each with one of the genes in the human genome. When the doctor calls you with the results, he’ 11 tell you which of thousands of human diseases you ’ re at risk for. If you have a defective gene that’ s placing you at risk for disease, he might treat you with a healthy version of the gene to make up for it, keeping you out of harm’ s way.
Soon, such diagnoses and treatments could be routine, says Mark Kay, MD, a professor of genetics at Stanford University School of Medicine and president of the American Society of Gene Therapy. "In five years, you may be able to go to referral centers and get gene therapy," he says. Although gene therapists have talked like that for a while, and the field has tremendous promise, so far they have demonstrably cured humans of just one disease; severe combined immunodeficiency(SCID). Known as the bubble-boy disease, it
decimates
the immune system and causes children to die young from infections. While the treatment looks promising, the virus used to deliver the gene in one trial may have activated a gene that causes cancer.
Such safety issues have dogged gene therapy. But gene therapists are pressing on. More than a dozen advanced clinical trials are underway that use genes to treat a variety of cancers, and other trials are ongoing for multiple sclerosis, AIDS and cystic fibrosis. Dr. Losordo has also begun a large trial of a gene therapy that seems to help patients regrow blood vessels that supply the heart— "grow your own bypass, if you will," he says. "It’ s a very exciting time. "
The best gene therapies just treat symptoms. The cells and tissues that make up our body still age, decay and die. "We know of no intervention that will slow, stop or reverse the aging process in humans," says Leonard Hayflick, PhD, professor of anatomy at the University of California, San Francisco, School of Medicine.
Also, lifesaving technologies and treatments don’ t come cheap, and sometimes terrible side effects emerge. "We will face some very difficult choices," says Thomas Murray, PhD, president of the Hastings Center in Garrison, New York, a think tank that explores ethical issues in biotechnology and health care. Fair enough. But perhaps it’ s OK, for now, to step back and marvel at just how far we’ ve come.
At the beginning of this passage, the author seems to indicate that gene therapy______.
选项
A、has been put into practice for ordinary diseases
B、will place people at risk for disease
C、could help human avoid thousands of diseases
D、can be done by your own doctor
答案
C
解析
文章第一段提到:通过基因检查,医生告诉你有得上千种疾病的危险,但是医生也可以帮助你治疗这些疾病,远离疾病威胁。也就是说,基因治疗可以帮助我们摆脱上千种疾病。
转载请注明原文地址:https://kaotiyun.com/show/lDU3777K
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