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  3. Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

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问题    Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【C1】______be applied fairly randomly or carelessly, but nowadays many believe that effective therapies need to be【C2】______and tailored to genetic faults in each individual’s cancer.
   However, a personalized treatment disregards the most fundamental reason why it is difficult to cure cancers【C3】______: cancer cells adapt and evolve【C4】______treatment. Even drugs that are initially effective often have a【C5】______diminishing effect, as the biological systems blocked by the treatment spontaneously compensate【C6】______re-routing the cancer cells’ internal wiring,【C7】______the cancer’s ability to spread. To use an【C8】______, traffic hot spots in towns can cause major traffic jams, but smart drivers will quickly find other short cuts. Then, in the absence of "short cuts", evolution【C9】______: naturally arising mutant cancer cells that are【C10】______the targeted drug rapidly outgrow their disabled siblings and cancer comes back.
【C4】
选项 A、in place of
B、in support of
C、in exchange for
D、in response to
答案D
解析 in place of：取代(instead of)；in support of：支持；in exchange for：交换；in response to：对……做出反应，响应……。该句的意义是：由于治疗，癌细胞逐渐适应环境并演化。
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