首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
Whenever I speak to educators and interested laypeople about neuroplasticity—the ability of the adult brain to change in functio
Whenever I speak to educators and interested laypeople about neuroplasticity—the ability of the adult brain to change in functio
admin
2016-06-30
92
问题
Whenever I speak to educators and interested laypeople about neuroplasticity—the ability of the adult brain to change in function and structure—one of the questions I often get is whether neuroplasticity can be tapped to treat truly devastating brain diseases such as Alzheimer’s or schizophrenia. After all, neuroplasticity has been used to treat stroke, depression, dyslexia, and other diseases or injuries of the brain. The jury is still out on Alzheimer’s(though since this disease involves massive neuronal death, my bet is that the answer will, sadly, be no). But to my surprise, the answer to schizophrenia might just be yes.
In schizophrenia, which affects about 1. 1 percent of American adults, patients suffer from visual and auditory hallucinations, delusions,an absence of emotion, and cognitive deficits. All told, that seemed to be just too much for an approach based on neuroplasticity, which involves retraining the brain, to handle.
But it turns out that at least some of the symptoms of schizophrenia can be lifted with brain training. In a study published in the July issue of the American Journal of Psychiatry, scientists led by Sophia Vinogradov of the University of California, San Francisco, describe what they call " neuroplasticity-based auditory training" to improve memory in people with schizophrenia. Basically, what they did was to assign 55 patients with schizophrenia to receive a cognitive-training program developed by Posit Science or to play a computer game that required just as much time and concentration. The Posit program, similar to one the company developed to improve memory in the elderly, emphasizes basic auditory and speech perception: participants used it one hour a day, five days a week, for ten weeks. The better they got, the harder the program got: it automatically adjusts the level of difficulty to keep the patients’ performance at a constant level so they stay engaged.
Fisher and her colleagues found that the brain-trained group showed noticeably bigger improvements in cognition and verbal working memory than the game-playing control group. The emphasis on auditory training reflects the belief of UCSF’s Michael Merzenich, a pioneer in neuroplasticity and cofounder of Posit, that this is the portal to improved memory and, possibly, cognition. The idea is that if you hear more clearly, then your brain makes fewer errors in encoding the information contained in speech.
It’s hard to argue with even preliminary success, odd as it seems that merely hearing better could bring about such improvements in memory(and not just memory for heard words: it improves memory for seen words as well). "This emphasis on perceptual processes is a critical insight of the Posit Science approach and a clear distinction from other cognitive-training programs," says Green. " The significance of the new study," he says, is that "it addresses cognitive training at a more basic neurobiological level than any previous strategy. We can hope that the dramatic effects they have reported will prove to be replicable and durable and that they will extend to meaningful effects for patients’ lives. "
Hope is all well and good. But schizophrenia is notable not only for its severity, but for the yawning gap between what’s known to be effective and what treatments patients actually receive. Green asks rhetorically, "if cognitive training for schizophrenia worked, would we not all know it by now?" In fact, researchers do know it, and some clinicians know it, but by one estimate fewer than 15 percent of schizophrenics get it(or other treatments, rehabilitation and support that would let them live independently). In fact, in a paper earlier this year in Schizophrenia Bulletin, scientists led by Robert S. Kern of the Geffen School of Medicine at the University of California, Los Angeles, were quite upbeat in their assessment of treatments for schizophrenia— none of them the problematic antipsychotic medications that in too many cases are all that people with schizophrenia receive.
Take cognitive-behavior therapy. Its basic premise is that people can be taught to think about their thoughts differently. It is effective in depression where people are taught to think about their tendency to catastrophize—"I had a bad date: no one will ever love me because I am worthless and unlovable". But in something as serious as schizophrenia? Yes, Kern and his colleagues find. It turns out that, with cognitive-behavior therapy, patients who hear voices and feel persecuted can learn to see these symptoms as almost normal in that many people experience them when, say, they are sleep deprived, under extreme stress, drunk or stoned or as "just" the manifestations of a neurobiological glitch and not real. The approach is surprisingly effective, a 2008 review found.
Similarly, exercises to improve attention, learning and memory, reasoning and problem-solving—which 90 percent of people with schizophrenia have problems with—also help, as this study found, and make a meaningful difference in whether the person can live independently and hold a job. The tragedy is that—due to an overburdened medical system, inadequate insurance and an inability to pay, as well as simply ignorance about how to find help—few patients with schizophrenia receive what works.
Which of the following is NOT the reason why patients of schizophrenia frequently cannot get effective treatments?
选项
A、There is too much for the medical system to do.
B、Some patients cannot afford the cost of the treatments.
C、Some patients just refuse to get help.
D、Some patients are not well-educated and can not find the way to get help.
答案
D
解析
事实细节题。根据最后一段最后一句可知,原文列举出很少有病人接受有效治疗的四个原因,[D]是对第四个原因的曲解,ignorance指的是“无知”,原文意为“仅仅是因为不知如何寻求帮助”,此处指寻求帮助方面的无知,而非知识水平的无知,[D]“有些病人受教育程度不高,不知如何寻求帮助”与原文不符,故为正确答案。[A]、[B]和[C]对原文中提到的另外三个原因分别进行了同义转述,均为精神分裂症病人无法得到有效救治的原因,故均可排除。
转载请注明原文地址:https://kaotiyun.com/show/tQ7O777K
0
专业英语八级
相关试题推荐
WheneverIspeaktoeducatorsandinterestedlaypeopleaboutneuroplasticity—theabilityoftheadultbraintochangeinfunctio
Associetychanges,socialvaluesandlinguisticvaluesbegintodiverge.Languagecontainstraditionalvalues—thisiswhichis
Associetychanges,socialvaluesandlinguisticvaluesbegintodiverge.Languagecontainstraditionalvalues—thisiswhichis
Associetychanges,socialvaluesandlinguisticvaluesbegintodiverge.Languagecontainstraditionalvalues—thisiswhichis
AcountrylikeBritaintodaysurvivesandprospersbythetalentandabilityofitspeople.Humancapitaliskey.Themoreitis
Thefunctionofthesentence"Iapologize"is
Allofthefollowingwordsbelongto"Broadening"insemanticchangeEXCEPT______
随机试题
胶管应平放或卷盘平放,下垫方木或木板,垛高不超过1m,储存期限内每()倒垛一次。
患儿,5个月。因发热、咳嗽两天、气喘1天入院。体检:T:39.5℃,P:150次/分,R:50次/分,烦躁不安,面色灰白,两肺有湿哕音。诊断:支气管肺炎。该患儿首选的护理诊断是
某女,38岁,近20天以来崩漏不止。于今晨起床时突然昏倒,面色苍白,口唇不华,汗出肢冷,呼吸微弱,舌淡脉芤。
化学结构为的药物名称是
急性早幼粒细胞白血病的免疫学检验髓系标志中为阳性的有()。
消费品市场是指()。
某在建商业大楼在钢结构施工中,必须按钢结构焊接规定进行焊接,还需进行焊接工艺试验和无损检验。根据以上内容,回答下列问题:钢结构的焊接方法包括哪些?
建设工程项目进度控制的目的是()。
区域保税的报核期限是()。
下列选项中,不属于美术教学设计的基本要素的是()。
最新回复
(
0
)