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  3. One of the great mystery of modern biology is how 【M1】______ proteins—the strings of amino acids that are the substance

One of the great mystery of modern biology is how 【M1】______ proteins—the strings of amino acids that are the substance

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问题    One of the great mystery of modern biology is how         【M1】______
proteins—the strings of amino acids that are the substance
of all living things—fold into precise and complex shapes
when they created inside living cells.                       【M2】______
   Proteins snap into their predestined shape within
microseconds, but the multistep process by which they do
so is so complicated that this would take a powerful computer【M3】______
centuries to come up a model for how it is done.             【M4】______
   Recently, however, some very smart chemists at
Stanford University and the University of Illinois borrowed
an idea from the SETI (Search for Extraterrestrial
Intelligence) project to find an alternate solution.         【M5】______
   The SETl @ home project divvies out to 4 million PC
owners chunks of raw data from the giant Arecibo radio
telescope in Puerto Rico. Those PCs, in its idle moments,    【M6】______
filter this electronic noise for telltale signs of another civilization
in the cosmos, and then ship the results back to SETI. Folding
@ home, the brainchild of Stanford biophysics Professor
Vijay Pende, similar parcels out the protein folding         【M7】______
computations among 43,000 active PC-owning volunteers.
In Sunday’s online version of the British journal Nature,
Pende reported success. The "distributed computing"
system has modeled how a man-made chain of 23 amino
acids called BBA5 snap into shape over the course of 6       【M8】______
microseconds matched the time it takes the protein to        【M9】______
form and fold in the lab.
   The PC network already is at work deciphering the
folding of real human proteins and may one day ravel        【M10】______
just what goes wrong in misshapen proteins believed
responsible for afflictions such as Creutzfeldt-Jakob and
Alzheimer’s disease.
【M4】
选项
答案∧ a—with
解析 come up with意为“产生；发现”，而come up则为“发生；出现”之意。
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