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Beyond the Pap Scientists have known for some time that virtually all cases of cervical cancer are triggered by a family of
Beyond the Pap Scientists have known for some time that virtually all cases of cervical cancer are triggered by a family of
admin
2014-09-12
35
问题
Beyond the Pap
Scientists have known for some time that virtually all cases of cervical cancer are triggered by a family of viruses called human papillomavirus, or HPV. Most women who become infected with HPV are able to shake off the virus and suffer no apparent long-term consequences to their health. But a few women develop a persistent infection that can, for reasons that are not entirely clear, eventually lead to cancerous changes in the cervix.
Now researchers at the Digene Corp. of Beltsville, Maryland, have developed a test that detects an active HPV infection by looking for its genetic byproducts in the vagina. The HPV test was better than the standard Pap test at finding cervical cancer at any stage, according to two studies published this month in the Journal of the American Medical Association. So far, so good. Unfortunately, the test’ s false-positive rate— how often it indicated that there was a problem when none existed—was almost twice as high as that for the Pap smear. In these cases, a biopsy of the woman’ s cervix showed no sign of disease.
And that’s the crux of the problem. How many women should undergo what is, when it comes right clown to it, unnecessary treatment to find a few more cases of cervical cancer? Shouldn’ t health officials focus instead on making sure that more women undergo regular Pap-smear examinations? After all, Pap smears, though far from perfect, have helped dramatically lower the death toll from cervical cancer, taking it from the No. 1 cause of death due to cancer in American women to the 10th.
Complicating matters is the fact that HPV is a very common infection. In some parts of the US as many as half of all women under age 35 have an active case. Yet 99 out of 100 women who are HPV-positive will never get cervical cancer, estimates Dr. Joanna Cain, vice president of the American College of Obstetricians and Gynecologists. "If those 99 women live their lives as if they’re going to develop cancer," she says, " we’ re not necessarily doing them any good.
At present, the HPV test is approved in the US only to help resolve ambiguous results from a Pap-smear test. Many gynecologists believe that HPV will eventually replace the Pap. But they’ re not willing to abandon it without a lot more detailed information and neither should you.
The HPV test was better than the standard Pap test in every aspect.
选项
A、Right
B、Wrong
C、Not mentioned
答案
B
解析
文章第二段前半部分内容主要描述了人类乳头状瘤病毒检测方法的优势。但在第四句中提到,这种试验的假阳性率是巴氏涂片试验假阳性率的两倍,故选B。
转载请注明原文地址:https://kaotiyun.com/show/wnhd777K
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