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医学
Dr. Beatrice Hahn of the University of Alabama at Birmingham announced that she’ d learned the origins of HIV-1, the virus respo
Dr. Beatrice Hahn of the University of Alabama at Birmingham announced that she’ d learned the origins of HIV-1, the virus respo
admin
2014-01-15
33
问题
Dr. Beatrice Hahn of the University of Alabama at Birmingham announced that she’ d learned the origins of HIV-1, the virus responsible for 99 percent of the world’ s 33million AIDS cases. Hahn and her colleagues were able to trace it specifically to a subspecies of chimpanzee called Pan troglodytes.
Chimps are not the only primates that carry viruses related to HIV. Earlier this decade scientists linked HIV-2 to a monkey called the sooty mangabey. Mandrills and African green monkeys carry still other simian immuno-deficiency viruses(SIVs). The closest links to HIV-1 seemed to be three viral samples isolated in chimpanzees. But one of the three was so divergent from the other two that scientists doubted they were HIV-1’ s immediate ancestors. To solve this puzzle, Hahn and her international team first had to fit the human and simian viruses into genetic "family trees" that accounted for their similarities and differences. They next had to show that the chimps were in the same region where AIDS got its start in humans. In fact, the chimp subspecies lives in West Central Africa, the region where HIV-1 is thought to have originated. There was even a plausible mode of transmission from chimp to human. The animals have long been hunted for food, so blood from the carcasses could easily have entered the hunters’ bodies through superficial wounds. Hahn’s group showed how, after jumping species on at least three occasions, chimpanzee SIV evolved into the three families of HIV-1 strains recognized today.
The question is not merely of academic interest. The chimps, it seems, carry their version of the virus but do not get sick from it. In theory at least, they could reveal important clues about controlling AIDS. "Humans share 98.5 percent of their genes with chimpanzees, points out Dr Feng Gao of UAB, one of Hahn’ s collaborators. But just as scientists are learning the chimps’ value in AIDS research, this critical subpopulation is being hunted to the brink of extinction. Not only does that mean hunters may be contracting additional viral strains; it also means that mankind is losing a living data-base of AIDS information. "It’ s like burning a whole library of books without having read them," says Hahn. Given the similarity of man and chimp, it could prove a tragic loss. Who knows what other mysteries may be answered in those books.
Which of the following could be the best title for this article?
选项
A、Fatal Diseases in West Central Africa.
B、The Chimp — a Possible Killer in West Central Africa.
C、How AIDS Began — Linking HIV-1 to Chimps in West Central Africa.
D、How HIV-1 Spreads in West Central Africa.
答案
C
解析
转载请注明原文地址:https://kaotiyun.com/show/ebT3777K
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