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Influenza and Vaccines There is no specific cure for influenza. Recommended treatment usually consists of bed rest and incre
Influenza and Vaccines There is no specific cure for influenza. Recommended treatment usually consists of bed rest and incre
admin
2012-01-14
55
问题
Influenza and Vaccines
There is no specific cure for influenza. Recommended treatment usually consists of bed rest and increased intake of nonalcoholic fluids until fever and other symptoms
lessen
in severity. Certain drugs have been found effective in lessening flu symptoms, but medical efforts aimed against the disease focus chiefly on prevention by means of vaccines that create immunity. No drugs can cure influenza, but certain antiviral medicines can relieve flu symptoms. Available by prescription, these drugs provide modest relief, but only if taken on the first or second day of symptoms. The drugs amantadine (sold under the brand name Symmetrel) and rimantadine (Flumadine), both in pill form, work against hemagglutinin and are effective in treating type A influenza. Two other drugs inhibit neuraminidase and are effective against both type A and type B strains: oseltamivir (Tamiflu) is in pill form and zanamivir (Relenza) is an inhalant. A flu vaccine consists of greatly weakened or dead flu viruses, or fragments of dead viruses. Antigens in the vaccine stimulate the patient’s immune system to produce antibodies against the viruses. If the flu viruses invade a vaccinated person at a later time, the sensitized immune system recognizes the antigens, produces the antibodies and quickly responds to help destroy
them
. About 5 to 10 percent of people who receive a flu vaccine experience
mild
, temporary side effects, typically soreness at the injection site. Young children who have not previously been exposed to the influenza virus are most likely to experience side effects. Flu viruses constantly change so different virus strains must be incorporated in vaccines from one year to the next. Scientists try to provide a good match between the vaccine and the most serious virus strains circulating at the time. But because it takes months to manufacture and distribute vaccines, decisions on their composition must be made well before the start of each flu season. Each February experts at the World Health Organization (WHO) recommend a vaccine composition to be used for the forthcoming winter in the Northern Hemisphere; a second recommendation is made in September for vaccines to be used in the Southern Hemisphere. Typically vaccines contain antigens from three virus strains, usually two strains from type A and one strain from type B. According to the CDC, the success of flu vaccines varies from one person to another. In healthy young adults, the vaccines are 70 to 90 percent effective in preventing the disease. In the elderly and people with certain chronic medical conditions, the vaccines are less effective in preventing illness but help reduce the severity of an infection and the risk of major complications or death. Studies show that flu vaccines reduce flu-related hospitalization by about 70 percent and flu-related deaths by about 85 percent among elderly people. The CDC recommends annual flu shots for people who are at high risk for developing serious complications as a result of an influenza infection.
(A) [■]This group includes all people aged 65 and older; people in nursing homes and other facilities that house people with chronic medical conditions; people with chronic heart, lung or kidney disease, diabetes, an impaired immune system, or severe forms of anemia; children and adolescents with conditions treated for long periods of time with aspirin (which makes them vulnerable to Reye’s syndrome) ; and women who will be in the second or third trimester of pregnancy during the influenza season.
(B) [■] Some doctors encourage individuals who travel to areas of the world where influenza viruses circulate to receive the most current vaccine.
(C) [■] Vaccination taken earlier can better protect the travellers from being infected by influenza in the epidemic areas
(D) [■] vaccination is more urgently needed particularly if they are at higher risk of complications It takes the human immune system one to two weeks after vaccination to develop antibodies to the flu antigens. According to the CDC, the best time to get flu shots in the United States is between October 1st and mid-November—sufficiently in advance of the peak of influenza activity, which in the United States generally lasts from late December until early March. Flu shots must be given
annually
for two reasons. First, antibody protection that is provided by the vaccine decreases during the year following vaccination. Second, vaccines created for pre-existing viral strains may not work against new strains; nor does an infection with one flu strain confer immunity to infection by another strain.
According to Paragraph 2, which of the following statements is true relating to the groups of drugs mentioned?
选项
A、The four drugs are different only in the form.
B、All four drugs work against one kind of virus.
C、The two groups of drugs inhibit different viruses.
D、Both groups of drugs are effective against type B.
答案
C
解析
本题也是事实信息题。题目问:根据第二段,下列关于几种流感药的论述哪项是正确的?文章共提到四种两组流感药,第一组amantadine和rimantadine可以抗击 hemagglutinin,能治疗A类流感,都是药片;第二组oseltamivir和zanamivir可以抗击neuraminidase,既能治疗A类流感,也能治疗B类流感,其中oseltamivir是片状,而zanamivir是液体。符合这些捕述的正确选项是C,即两组药物抵抗不同的病毒,故选C项。
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