首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without ca
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without ca
admin
2018-06-06
53
问题
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without causing side effects in an early study of a dozen patients. The gene therapy treatment involved slipping billions of copies of a gene into the brain to calm overactive brain circuitry. More than half a million Americans have Parkinson’s. They endure symptoms that include tremors, rigidity in their limbs, slowness of movement and impaired balance and coordination. Eventually they can become severely disabled.
The small study focused on testing the safety of the procedure rather than its effectiveness, and experts cautioned it’s too soon to draw conclusions about how well it works. But they called the results promising and said the approach merits further studies. "We still have quite a bit more testing to do," said Dr. Michael Kaplitt of Weill Cornell Medical College in New York, an author of the study. Still, "the initial results are extremely encouraging".
Nathan Klein, a 59-year-old freelance television producer in Port Washington, N.Y., said the disease left him "pretty messed up". It weakened his voice, impaired his walking and made his hand tremble so badly he couldn’t hold a glass of wine without spilling it all. Klein was the first patient to be treated with Kaplitt’s gene therapy procedure in 2003, and he said his symptoms gradually subsided afterward. Nowadays, he said, apart from freezing now and then when he wants to walk, the symptoms are basically gone. "I’m elated," said Klein, who continues to take his regular pills for the disease. "It’s unbelievable."
Kaplitt, who has a financial interest in Neurologix Inc., which paid for the research, noted that the 12 patients in the study still have Parkinson’s symptoms. The amount of medication they were already taking for their symptoms didn’t change significantly in the year after the surgery. Current medicines can control symptoms, but can’t stop the disease from getting worse over time, and they can produce troublesome side effects like uncontrollable movement.
Some patients gain relief from a surgical treatment called deep brain stimulation, in which electrodes are placed in the brain and connected to a programmable stimulator. Kaplitt’s procedure was aimed at achieving the same goal as that surgery, calming overactive circuitry in the brain. It gets overactive because it loses the normal supply of a chemical called GABA. The gene therapy was designed to make the brain produce more GABA.
For the gene therapy surgery, a tube about the width of a hair was threaded through a hole about the size of a quarter at the top of the skull. The tube delivered a dose of a virus engineered to ferry copies of a gene into cells of a brain region called the subthalamic nucleus. The gene copies enable the cells to pump out more GABA.
The symptoms of Parkinson’s disease are as follows EXCEPT______.
选项
A、tremors
B、stiffness in patients’ limbs
C、slowness of movement
D、impaired thinking ability
答案
D
解析
转载请注明原文地址:https://kaotiyun.com/show/cESO777K
本试题收录于:
NAETI中级口译笔试题库外语翻译证书(NAETI)分类
0
NAETI中级口译笔试
外语翻译证书(NAETI)
相关试题推荐
Volunteeringonpoliticalcampaignscanhelpstudentsbecomeamoreattractivecandidateforjobsingovernment.
InNorthAmerica,Nebraskapioneeredinthatwhichistobecomethearea’schiefeconomicactivity,agriculture.
Chinaisthetopsourcecountryofinternationalstudentsintheworld.Recentstatisticshaveshowna【C1】______trendforChine
Declininghouseprices,risingjoblayoffs,skyrocketingoilcostsandamajorcreditcrunchhavebroughtconsumerconfidenceto
Howmuchphysicalactivityshouldteenagersdo,andhowcantheygetenough?Manyteenagersspendalot
People’snatural"flightorfight"responsewillbeautomatedwhen______withthephobiasource.
下面你将听到外商有关中国零售业发展情况的一段讲话。China’seconomy,oncereliantonstatespendinginheavyindustry,hasincreasinglylookedtothe
《北京2008》和大家见面了!在对这份精美的杂志表示衷心祝贺的同时,希望它更好地反映2008年北京奥运会的筹备情况,展示北京东方文明故都的城市风貌、厚重的历史、灿烂的文化和充满生机的现代气息,使这份刊物成为增强我们同国际奥林匹克大家庭之间联系的桥梁和纽带。
下面你将听到的是一段有关中国教育改革与发展的讲话。党的十一届三中全会以来,随着党和国家工作重点转移到以经济建设为中心。教育在社会主义现代化建设中的地位和作用也越来越重要,我国教育的改革和发展取得了很大的成就。进入20世纪90年代,科学
联合国的成立及《联合国宪章》宗旨与原则的确立,在维护世界和平、促进社会发展的同时,也推动了奥林匹克精神的传播与发扬。
随机试题
流行性出血热早期低血压的主要原因是( )。
回归热可见于哪种疾病()
一般不选用低盐饮食的疾病是()。
下列关于材料设备由承包人采购的方式的说法中正确的有()。
绞吸式挖泥船的基本施工方法是()。
关于渠道衬砌,下列说法正确的是()。
建立账套时需要指定的基本信息中没有()。
出境快件在其运输工具离境( )小时前向离境口岸检验检疫机构办理报检手续。
Theenvironmentiseverythingthatsurroundsus:plants,animals,buildings,country,air,water—literallyeverythingthatcana
在对计算机系统安全等级的划分中,Unix属于哪一级?()
最新回复
(
0
)