首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without ca
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without ca
admin
2018-06-06
45
问题
An experimental treatment for Parkinson’s disease seemed to improve symptoms—dramatically so, for one 59-year-old man—without causing side effects in an early study of a dozen patients. The gene therapy treatment involved slipping billions of copies of a gene into the brain to calm overactive brain circuitry. More than half a million Americans have Parkinson’s. They endure symptoms that include tremors, rigidity in their limbs, slowness of movement and impaired balance and coordination. Eventually they can become severely disabled.
The small study focused on testing the safety of the procedure rather than its effectiveness, and experts cautioned it’s too soon to draw conclusions about how well it works. But they called the results promising and said the approach merits further studies. "We still have quite a bit more testing to do," said Dr. Michael Kaplitt of Weill Cornell Medical College in New York, an author of the study. Still, "the initial results are extremely encouraging".
Nathan Klein, a 59-year-old freelance television producer in Port Washington, N.Y., said the disease left him "pretty messed up". It weakened his voice, impaired his walking and made his hand tremble so badly he couldn’t hold a glass of wine without spilling it all. Klein was the first patient to be treated with Kaplitt’s gene therapy procedure in 2003, and he said his symptoms gradually subsided afterward. Nowadays, he said, apart from freezing now and then when he wants to walk, the symptoms are basically gone. "I’m elated," said Klein, who continues to take his regular pills for the disease. "It’s unbelievable."
Kaplitt, who has a financial interest in Neurologix Inc., which paid for the research, noted that the 12 patients in the study still have Parkinson’s symptoms. The amount of medication they were already taking for their symptoms didn’t change significantly in the year after the surgery. Current medicines can control symptoms, but can’t stop the disease from getting worse over time, and they can produce troublesome side effects like uncontrollable movement.
Some patients gain relief from a surgical treatment called deep brain stimulation, in which electrodes are placed in the brain and connected to a programmable stimulator. Kaplitt’s procedure was aimed at achieving the same goal as that surgery, calming overactive circuitry in the brain. It gets overactive because it loses the normal supply of a chemical called GABA. The gene therapy was designed to make the brain produce more GABA.
For the gene therapy surgery, a tube about the width of a hair was threaded through a hole about the size of a quarter at the top of the skull. The tube delivered a dose of a virus engineered to ferry copies of a gene into cells of a brain region called the subthalamic nucleus. The gene copies enable the cells to pump out more GABA.
The symptoms of Parkinson’s disease are as follows EXCEPT______.
选项
A、tremors
B、stiffness in patients’ limbs
C、slowness of movement
D、impaired thinking ability
答案
D
解析
转载请注明原文地址:https://kaotiyun.com/show/cESO777K
本试题收录于:
NAETI中级口译笔试题库外语翻译证书(NAETI)分类
0
NAETI中级口译笔试
外语翻译证书(NAETI)
相关试题推荐
Neverwehadseenanythinglikethisstyleofarchitecturebefore,wethoughtwewerelookingatgiantsculptures,notbuildings
Chinaisthetopsourcecountryofinternationalstudentsintheworld.Recentstatisticshaveshowna【C1】______trendforChine
Whentheydeviatedfromthediet,evenafteryearsofcompliance,thediseaseinvariablygotworse.
Infact,morethan75percentofallmajorcorporationsreportthattheymonitortheiremployees’useofE-mailandInternetacc
WorldBankTheWorldBankisoneofthelargestsuppliersofdevelopmentassistance.Itsmaingoalistoimprovelivingcond
WorldWaterShortageAnewstudywarnsthataboutthirtypercentoftheworld’speoplemaynothaveenoughwaterbytheyear
VisitorstoBritainmayfindthebestplacetosamplelocalcultureisinatraditionalpub.Butthesefriendlyhostelriescanb
当前,亚欧两地区都处于蓬勃发展的阶段。亚洲是世界上最具经济活力的地区,资源丰富,市场广阔,区域合作方兴未艾。欧盟是世界上最大的发达经济体,资本充裕,科技先进,一体化程度高。两地区政治上共识很多,经济上优势互补,文化上各具特色,为开展更广泛和具有实质性的对话
WhichofthefollowingisNOTtrueaboutonlinemarketplaces?
ComputersmonitoreverythinginSingaporefromsoilcompositiontolocationofmanholes.Attheairport,ittookjust15seconds
随机试题
滑铁卢桥地处泰晤士河弯曲处。桥上视野开阔,是游客们喜欢拜访的地方。1899年到1901年之间,旅居伦敦的印象派画家莫奈就以该桥为主题,创作了一系列画作。这些画的视角相似,构图也几乎一模一样,差别只是天气状况和相应的光影色彩变化。一直以来,莫奈作画的精确位置
25岁就诊患者,口腔卫生情况不佳,左下第一恒磨牙患有牙髓一牙周联合病变,疼痛剧烈,但患牙无松动。另外,还应嘱咐病人做好口腔保健,除了
A.肌肉疼痛 B.脱水热 C.吞咽困难 D.尿钠测不出 E.四肢麻木只有重度高渗性脱水可见的症状是
李村的甲在放羊时因一时大意,没能发现自己的一头羊走失。张村的乙在回家的路上发现该羊,误以为是自家前不久走失的羊。遂将其带回家并进行饲养。当夜,该羊被闯入羊圈的毒蛇咬死,此时该羊市价1000元。第二日,乙发现该羊并非自己的,虽将其打理出售,得1200元。数日
2014年3月1日,政府拨付A公司1000万元财政拨款(同日到账),要求用于购买大型科研设备1台;并规定若有结余,留归公司自行支配。2014年4月1口,A公司购入大型设备,以银行存款支付实际成本为960万元,同日采用出包方式委托丙公司开始安装。2014年4
研究者认为,人的价值观刚开始就能被个体清醒地意识到。()
为狩猎运动辩护的一个普遍说法是认为它起到了重要的管理野生动物的作用,如果没有它,无数动物将遭受饥饿和疾病。该辩护导致一个太过草率的结即狩猎运动,产生了一个更健康的动物群体。下面哪一项,如果正确,最好地支持了作者的立场,即狩猎运动不一定能产生一个更健康的动物
Thegrowthofthelimitedliabilitycompanyandmunicipalbusinesshadimportantconsequences.Suchlarge,impersonalmanipulati
A、Thereisavisitoratthedoor.B、ThewomaniscallingJack.C、Thedoorisopen.D、Thetelephoneisringing.AM:Someoneiskn
TOEICistheTestofEnglishforInternationalCommunication.Itmeasuresthe【B1】______ofpeopletocommunicateintheworkplac
最新回复
(
0
)