In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.

admin2022-11-16  69

问题     In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.【C1】________. in 2012, MERS was identified. In 2019, SARS-CoV-2【C2】________.
    Hundreds of other coronaviruses are known to be【C3】________in bats and other animals. Scientists have warned that some of them could arise in the future and【C4】________infect people. Our current COVID-19 vaccines were specifically【C5】________for SARS-CoV-2, but what if a next-generation vaccine could protect【C6】________both known and unknown coronaviruses?
    Scientists at the Walter Reed Army Institute of Research are working on a so-called universal coronavirus vaccine. Dr. Kayvon Modjarrad is【C7】________the effort. They have developed a vaccine specifically for SARS-CoV-2, and found that the immune response that it【C8】________is active against all the variants, as well as other coronaviruses like SARS-CoV-1. And this gives them confidence that it can be a platform for the entire coronavirus family.
    The vaccine is known as SpFN, which combines nanoparticles from ferritins with coronavirus spike proteins. But making the vaccine wasn’t as【C9】________as attaching one protein to another. Modjarrad and his colleagues had to【C10】________which parts of the spike to attach to which type of ferritin and how to【C11】________the two proteins together. It took months of trying more than 200 different【C12】________. By June of last year, the team found one version that succeeded where others had failed. They then【C13】________the experimental vaccine in mice and monkeys.
    The team also turned to less【C14】________animals for testing. Working with scientists in India, they【C15】________horses with the vaccine to learn how strong the【C16】________response was. And they【C17】________with Helen Dooley at the University of Maryland to vaccinate sharks—which make special antibodies.
    The results are【C18】________. but animals aren’t people. The Army vaccine is now being tested in a small, early-stage trial in humans.【C19】________it works and is safe, it could lay the【C20】________for a universal coronavirus vaccine.
【C10】

选项 A、point out
B、turn out
C、figure out
D、carry out

答案C

解析 空格所在部分为Modjarrad and his colleagues had to________which parts of the spike to attach to which type of ferritin (莫德贾拉德和他的同事们必须________刺突蛋白的哪一部分与哪一种铁蛋白相结合)。前一句已说到making the vaccine wasn’t as________as attaching one protein to another (制造疫苗并不像把一种蛋白质与另一种蛋白质相结合那么简单),可见研究人员必须努力弄清楚如何结合两种蛋白质,所以选择C项figure out“弄清楚,弄明白”。A项“指出”,B项“关掉;熄灭”,D项“执行;开展”,均无法与上下文构成合理的语意逻辑,故排除。
转载请注明原文地址:https://kaotiyun.com/show/4IMD777K
0

最新回复(0)